Optimizing Peptide Synthesis: The Role of Fmoc-Orn(Boc)-OH
In the intricate world of peptide synthesis, the selection of high-quality protected amino acid derivatives is paramount. Among these, Nalpha-Fmoc-Ndelta-Boc-L-ornithine (CAS: 109425-55-0) stands out as a vital building block. This article delves into why this specific ornithine derivative is indispensable for researchers and manufacturers in the pharmaceutical and biotechnology sectors. We will explore its chemical properties, applications, and the importance of sourcing it from a dependable supplier.
Understanding Nalpha-Fmoc-Ndelta-Boc-L-ornithine
Nalpha-Fmoc-Ndelta-Boc-L-ornithine is a modified form of the amino acid ornithine, featuring two crucial protecting groups. The Fmoc (9-fluorenylmethoxycarbonyl) group protects the alpha-amino group, while the Boc (tert-butoxycarbonyl) group shields the delta-amino group on the side chain. This dual protection allows for sequential and controlled addition of amino acids during peptide chain elongation, a cornerstone of solid-phase and solution-phase peptide synthesis. Its molecular formula is C25H30N2O6, with a molecular weight of approximately 454.52 g/mol. Typically presented as a white to off-white powder, its purity is a critical factor for successful synthesis.
Key Applications in Research and Development
The primary utility of Nalpha-Fmoc-Ndelta-Boc-L-ornithine lies in its role as an intermediate in the synthesis of complex peptides. These peptides are fundamental to numerous applications:
- Peptide-Based Pharmaceuticals: Many modern therapeutic drugs are peptide-based, targeting a wide range of diseases. Nalpha-Fmoc-Ndelta-Boc-L-ornithine is integral to constructing these therapeutically active peptide sequences.
- Drug Discovery Libraries: For researchers in drug discovery, creating diverse peptide libraries is essential for screening potential drug candidates. This derivative facilitates the efficient generation of such libraries.
- Biomaterials and Diagnostics: Modified peptides can serve as advanced biomaterials or components in diagnostic kits. The controlled synthesis enabled by this compound is key here.
- Custom Peptide Synthesis: Academic institutions and private research labs often require custom-synthesized peptides for specific projects, making reliable access to protected amino acids like Nalpha-Fmoc-Ndelta-Boc-L-ornithine crucial.
Why Partner with a Trusted Manufacturer?
For procurement professionals and R&D scientists, sourcing Nalpha-Fmoc-Ndelta-Boc-L-ornithine requires a supplier that guarantees high purity and consistent quality. Impurities can lead to low yields, failed syntheses, and inaccurate research results, ultimately wasting valuable time and resources. Therefore, choosing a reputable manufacturer and supplier is not just about price, but about ensuring the integrity of your research and production processes. If you are looking to buy Nalpha-Fmoc-Ndelta-Boc-L-ornithine, consider the benefits of working with experienced chemical manufacturers in China, who often provide competitive pricing and a stable supply chain.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical intermediates. Our Nalpha-Fmoc-Ndelta-Boc-L-ornithine, CAS: 109425-55-0, is manufactured under strict quality controls, ensuring it meets the demanding requirements of peptide synthesis. We invite you to contact us for a quote and sample to experience the difference that quality and reliability make in your procurement of essential pharmaceutical intermediates.
Perspectives & Insights
Molecule Vision 7
“Understanding Nalpha-Fmoc-Ndelta-Boc-L-ornithineNalpha-Fmoc-Ndelta-Boc-L-ornithine is a modified form of the amino acid ornithine, featuring two crucial protecting groups.”
Alpha Origin 24
“The Fmoc (9-fluorenylmethoxycarbonyl) group protects the alpha-amino group, while the Boc (tert-butoxycarbonyl) group shields the delta-amino group on the side chain.”
Future Analyst X
“This dual protection allows for sequential and controlled addition of amino acids during peptide chain elongation, a cornerstone of solid-phase and solution-phase peptide synthesis.”