Organic synthesis is the backbone of modern chemical innovation, enabling the creation of novel materials, pharmaceuticals, and agrochemicals. For chemists striving for efficiency and precision, the selection of versatile building blocks is paramount. 5-Bromo-2-fluorobenzoic acid (CAS 146328-85-0) emerges as an indispensable tool in the synthetic chemist's arsenal, offering a unique combination of functional groups that facilitate a wide array of transformations. As a specialized manufacturer and supplier of fine chemicals, we provide this critical intermediate and insights into its effective utilization in synthesis.

The molecular structure of 5-Bromo-2-fluorobenzoic acid is particularly advantageous for complex organic synthesis. The carboxylic acid group allows for straightforward derivatization, such as esterification or amidation, while the ortho-fluorine and para-bromine substituents imbue the aromatic ring with distinct reactivity patterns. The bromine atom, in particular, is an excellent leaving group, making it highly susceptible to nucleophilic aromatic substitution and, more importantly, palladium-catalyzed cross-coupling reactions. These reactions, including Suzuki-Miyaura coupling with boronic acids, Heck reactions with alkenes, and Sonogashira couplings with alkynes, are cornerstones of modern synthetic methodology. They enable chemists to efficiently construct complex carbon frameworks, often with high stereoselectivity and functional group tolerance.

When planning your synthetic route, consider the benefits of incorporating 5-Bromo-2-fluorobenzoic acid. Its availability in high purity from reliable suppliers, such as ourselves, ensures reproducible results in your laboratory. We offer this product with a purity of ≥ 97% (GC), guaranteeing its suitability for demanding synthetic protocols. Furthermore, understanding pricing and bulk purchasing options can significantly impact project budgets. As a China-based manufacturer, we provide competitive pricing, allowing researchers and chemical companies to buy this essential intermediate economically, supporting both R&D initiatives and larger-scale production runs. It’s crucial to work with a supplier who provides comprehensive product specifications and safety data sheets (SDS) to ensure safe handling and optimal use.

For chemists seeking to push the boundaries of synthetic chemistry, 5-Bromo-2-fluorobenzoic acid offers a reliable and versatile platform. Its dual halogenation and carboxylic acid functionality open doors to a vast array of synthetic possibilities. We encourage you to explore the potential of this building block in your next project. If you are interested in learning more about its applications or wish to purchase 5-Bromo-2-fluorobenzoic acid from a trusted manufacturer and supplier, please do not hesitate to contact us. We are dedicated to empowering chemists with the high-quality materials needed for groundbreaking discoveries.