In the dynamic field of molecular biology and neuroscience, researchers continually seek specialized compounds that unlock deeper insights into biological processes. PE 22-28, a precisely engineered peptide, has emerged as a crucial tool for those investigating the function of TREK-1 channels and their implications in various physiological and pathological states. This article provides an overview of PE 22-28, highlighting its scientific significance, key applications, and essential guidance for researchers looking to purchase this vital scientific reagent.

PE 22-28, identified by its CAS number 1801959-12-5, is a peptide recognized for its potent inhibitory activity against TREK-1 (TWIK-related acid-soluble domain-containing potassium channel 1). TREK-1 channels are widely distributed in the nervous system and play critical roles in regulating neuronal excitability, pain signaling, and mood. The high specificity and potency of PE 22-28, demonstrated by its low IC50 value of 0.12 nM, make it an ideal compound for researchers who require precise control over TREK-1 channel activity in their experimental setups. This level of specificity is crucial for obtaining reliable and interpretable research data.

The scientific applications of PE 22-28 are extensive and continue to expand. It is particularly valuable in depression research, as studies suggest that TREK-1 channel activity is linked to mood regulation, and inhibition by PE 22-28 can elicit antidepressant-like effects. Furthermore, PE 22-28 has shown promise in the area of neuroprotection. Research indicates its potential to reduce neuronal damage and promote neurogenesis, offering insights into recovery processes following ischemic events or other neurological insults. These applications underscore PE 22-28's importance in advancing our understanding of neurological disorders and developing potential therapeutic interventions.

For research scientists and institutions requiring PE 22-28, sourcing from a reputable manufacturer is paramount to ensure the quality and consistency of the product. We are a dedicated manufacturer and supplier of high-purity research peptides, including PE 22-28, with purity levels often exceeding 99%. We provide comprehensive technical documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS), to support your research needs. When deciding where to buy PE 22-28, it is advisable to choose suppliers with a proven track record in peptide synthesis and quality assurance.

The availability of PE 22-28 empowers researchers to conduct in-depth studies on TREK-1 channel function, neurological diseases, and potential drug discovery pathways. We are committed to supporting the scientific community by offering this critical research peptide with competitive pricing and reliable availability. For those looking to buy PE 22-28, we encourage inquiries about our product offerings, bulk discounts, and custom synthesis services, ensuring you receive the highest quality materials for your groundbreaking research.

In summary, PE 22-28 is an indispensable peptide for researchers focused on TREK-1 channels and their role in neurological health. Its potent inhibitory action, demonstrated therapeutic potential in depression, and neuroprotective benefits make it a cornerstone compound. We stand ready to be your trusted supplier for high-quality PE 22-28, contributing to the progress of scientific discovery in neuroscience and beyond.