Exploring Peptide Modifications: The Advantage of Fmoc-D-2-Chlorophenylalanine
The field of peptide science is constantly evolving, driven by the demand for more sophisticated and targeted therapeutic agents. Central to this progress is the ability to precisely modify peptide structures. Fmoc-D-2-Chlorophenylalanine, a specialized protected amino acid derivative, offers significant advantages for researchers in peptide synthesis and modification. This article highlights its utility and the benefits of sourcing it from a reliable manufacturer.
Fmoc-D-2-Chlorophenylalanine, identified by its CAS number 205526-22-3, is a non-canonical amino acid widely used in peptide chemistry. Its structure combines the reliable Fmoc protecting group, essential for controlled peptide chain elongation, with a D-phenylalanine backbone featuring a chlorine atom substitution on the phenyl ring. This chlorination is key to imparting unique properties to synthesized peptides, influencing their conformation, receptor interactions, and resistance to enzymatic degradation. Researchers often seek to buy Fmoc-D-2-Chlorophenylalanine for precise structural modifications.
The advantages of using Fmoc-D-2-Chlorophenylalanine in peptide synthesis are manifold. Firstly, its incorporation allows for the introduction of a halogen atom, which can serve as a handle for further chemical modifications or as a structural element that modulates electronic properties and binding characteristics. This is particularly valuable in drug discovery, where fine-tuning these properties is critical for optimizing efficacy and safety. As a trusted Fmoc-D-2-Chlorophenylalanine supplier China, we ensure that this intermediate is available with high purity, meeting the stringent demands of advanced research.
The specific placement of the chlorine atom in the 2-position of the phenyl ring can influence the overall electronic distribution and steric bulk of the side chain. This can lead to altered peptide folding and improved binding to target biomolecules. Consequently, researchers undertaking custom peptide synthesis with chlorinated amino acids often choose this derivative to achieve specific structural or functional outcomes. Understanding the CAS 205526-22-3 price is essential for project planning, and we provide competitive pricing to facilitate your research endeavors.
In addition to its direct application in peptide synthesis, Fmoc-D-2-Chlorophenylalanine can be a crucial intermediate in the synthesis of peptidomimetics or small molecules designed to mimic peptide functions. Its availability from a dedicated manufacturer ensures a stable supply chain for ongoing research and development projects, supporting the progression from laboratory discovery to potential therapeutic applications.
For those seeking to enhance their peptide synthesis capabilities with modified amino acids, partnering with a knowledgeable and reliable supplier is essential. We are committed to providing high-quality Fmoc-D-2-Chlorophenylalanine, backed by robust quality control and dedicated customer service. Contact us to learn how we can support your research needs and provide you with this vital building block.
Perspectives & Insights
Alpha Spark Labs
“Its structure combines the reliable Fmoc protecting group, essential for controlled peptide chain elongation, with a D-phenylalanine backbone featuring a chlorine atom substitution on the phenyl ring.”
Future Pioneer 88
“This chlorination is key to imparting unique properties to synthesized peptides, influencing their conformation, receptor interactions, and resistance to enzymatic degradation.”
Core Explorer Pro
“Researchers often seek to buy Fmoc-D-2-Chlorophenylalanine for precise structural modifications.”