In the pharmaceutical industry, maintaining the highest standards of quality and safety is non-negotiable. This involves not only ensuring the purity of active ingredients but also meticulously controlling any potential impurities. 4-Hydroxy-D-phenylglycine (CAS 22818-40-2) plays a dual role: as a vital synthesis intermediate and as a crucial reference standard for pharmaceutical quality control. For R&D scientists and quality assurance managers, understanding its significance is key.

While primarily known as a chiral building block for antibiotics like amoxicillin and cefadroxil, 4-Hydroxy-D-phenylglycine also serves as a benchmark impurity in the production of these drugs. Pharmaceutical regulations mandate the identification and quantification of impurities, and using a certified reference standard is essential for accurate analytical testing. When you buy this compound for this purpose, partnering with a reputable manufacturer or supplier that provides certified, high-purity material is critical.

The availability of high-purity 4-Hydroxy-D-phenylglycine (≥ 99.00%) ensures that analytical methods used for impurity profiling are precise and reliable. This compound’s well-defined physical properties and solubility characteristics make it suitable for various analytical techniques employed in quality control laboratories. For pharmaceutical companies, ensuring a consistent supply of this standard from trusted sources, particularly from experienced Chinese manufacturers, is a vital aspect of their quality management systems.

Procuring this intermediate as an impurity standard requires specific attention to documentation, such as a detailed Certificate of Analysis that confirms its identity and purity for analytical use. When inquiring about price and availability, clearly state its intended use as a reference standard. Reliable suppliers will be equipped to provide the necessary certifications and support, ensuring your quality control processes are robust and compliant with regulatory requirements.