For many R&D departments and production facilities, understanding the cost landscape of essential chemical intermediates is as critical as their chemical properties. 2-Bromo-5-fluoro-isonicotinonitrile (CAS: 1256822-16-8), a vital component in pharmaceutical and fine chemical synthesis, is no exception. This article delves into the factors affecting its price and how procurement professionals can secure the best value when purchasing from Chinese manufacturers.

Factors Influencing the Price of 2-Bromo-5-fluoro-isonicotinonitrile

Several key elements contribute to the final price of 2-Bromo-5-fluoro-isonicotinonitrile:

  • Purity Level: As with most chemical intermediates, higher purity grades command higher prices. For applications demanding stringent quality, such as pharmaceutical synthesis, a minimum purity of 97% is typically expected, influencing the cost.
  • Order Volume: The per-unit price almost always decreases with larger order quantities. Bulk purchases, ranging from kilograms to metric tons, generally benefit from significant discounts compared to gram-scale orders for laboratory research.
  • Manufacturing Costs: The complexity of synthesis, raw material costs, energy consumption, and labor expenses in the manufacturing region all play a role. Chinese manufacturers often leverage economies of scale and efficient production processes to offer competitive pricing.
  • Supplier Margins and Overhead: Different suppliers will have varying cost structures, including research and development investments, quality control measures, marketing, and logistical overhead.
  • Market Demand and Supply Fluctuations: Like any commodity, the price of 2-Bromo-5-fluoro-isonicotinonitrile can be influenced by global demand and the overall availability of key raw materials used in its production.
  • Packaging and Shipping Costs: The cost of specialized packaging (e.g., for sensitive or hazardous materials) and international shipping also contributes to the final delivered price.

Securing Cost-Effective Solutions from China

China's chemical industry offers a highly competitive market for intermediates like 2-Bromo-5-fluoro-isonicotinonitrile. To obtain the best possible price, procurement managers should:

  • Request Multiple Quotes: Contact several Chinese manufacturers and suppliers to compare pricing for your required quantity and purity specifications.
  • Inquire About Bulk Discounts: Clearly state your anticipated annual or project-based volume to leverage scale-based pricing.
  • Evaluate Supplier Reliability: While price is important, consider the supplier's track record, quality assurance, and ability to deliver consistently. A slightly higher price from a reliable supplier often proves more cost-effective in the long run.
  • Consider Shipping and Incoterms: Understand the shipping costs and terms (e.g., FOB, CIF) to accurately assess the total landed cost.
  • Explore Free Samples: Many reputable suppliers offer free samples, allowing you to assess quality before committing to a larger purchase. This is a vital step in managing risk and ensuring cost-effectiveness.

Companies like NINGBO INNO PHARMCHEM CO.,LTD. are known for offering competitive pricing on high-quality pharmaceutical intermediates. By conducting thorough research and strategic negotiation, buyers can effectively manage their procurement costs for critical compounds such as 2-Bromo-5-fluoro-isonicotinonitrile, ensuring both project viability and budgetary adherence.