Procurement managers in the chemical and pharmaceutical sectors face the constant challenge of sourcing high-quality, reliable intermediates at competitive prices. 4-Bromo-1-fluoro-2-iodobenzene (CAS 116272-41-4) is a prime example of a critical building block whose availability and quality directly impact research and development timelines and outcomes. This article aims to guide procurement specialists on understanding this compound's value and effectively sourcing it, particularly from China.

Understanding the Chemical and Its Value Proposition

4-Bromo-1-fluoro-2-iodobenzene is a tri-halogenated aromatic compound with the molecular formula C6H3BrFI. Its significance lies in its multifaceted reactivity, driven by the presence of fluorine, bromine, and iodine atoms. These halogens allow for selective participation in various synthetic transformations, most notably palladium-catalyzed cross-coupling reactions. This makes it an indispensable intermediate for constructing complex organic molecules, including:

  • Pharmaceutical intermediates: Crucial for synthesizing APIs and novel drug candidates.
  • Agrochemical precursors: Used in developing new crop protection agents.
  • Advanced materials: Essential for creating organic electronic materials and specialty polymers.

For R&D purposes, a minimum purity of 97% is often specified to ensure predictable and reproducible experimental results. Procurement managers must ensure that the product meets these stringent quality standards.

Key Considerations for Procurement

When looking to buy 4-Bromo-1-fluoro-2-iodobenzene, several factors are critical:

  • Purity: Always verify the specified purity level (e.g., 97% min.) and request Certificates of Analysis (CoA) from suppliers.
  • Supplier Reliability: Partner with established manufacturers and suppliers known for consistent quality and on-time delivery.
  • Pricing: Obtain quotes from multiple sources to ensure competitive pricing, factoring in shipping and any import duties. Comparing 4-Bromo-1-fluoro-2-iodobenzene prices from different suppliers is a standard procurement practice.
  • Technical Support: A good supplier will offer technical assistance and be knowledgeable about the product's properties and applications.
  • Logistics: Understand lead times and shipping options to ensure timely arrival for your projects.

Sourcing from China: Strategic Advantages

China is a global leader in chemical manufacturing, offering significant advantages for sourcing intermediates like 4-Bromo-1-fluoro-2-iodobenzene. Chinese manufacturers often provide cost-effective solutions due to economies of scale and efficient production processes. When you search for a chemical synthesis reagent supplier in China, focus on those with a proven track record, robust quality management systems, and clear communication channels.

To effectively secure your supply, reach out to potential suppliers with specific requests, including CAS number (116272-41-4), desired quantity, purity requirements, and delivery timelines. This allows them to provide accurate quotes and assess their capacity to meet your needs.

In summary, securing a reliable supply of high-quality 4-Bromo-1-fluoro-2-iodobenzene is crucial for R&D success. By diligently researching and partnering with reputable manufacturers and suppliers, particularly those in China, procurement managers can ensure efficient and cost-effective acquisition of this vital chemical intermediate.