When engaging in complex organic synthesis, the reliable procurement of high-quality chemical intermediates is paramount. For professionals in the pharmaceutical and agrochemical sectors, 4-Chlorobutyryl Chloride (CAS 4635-59-0) stands out as a critical building block. Understanding how to effectively source this reactive acyl chloride can significantly impact your production efficiency and product quality. This guide aims to equip you with the essential knowledge for identifying and purchasing 4-Chlorobutyryl Chloride, emphasizing the benefits of partnering with reputable manufacturers and suppliers, particularly those based in China.

Understanding 4-Chlorobutyryl Chloride: Properties and Applications

4-Chlorobutyryl Chloride, with the chemical formula C4H6Cl2O and CAS number 4635-59-0, is characterized by its clear, colorless to yellow liquid appearance and pungent odor. Its dual functionality, featuring both a reactive acyl chloride group and a terminal chlorine atom, makes it highly versatile in various chemical transformations. This reactivity allows it to participate efficiently in acylation, esterification, and amidation reactions.

The primary utility of 4-Chlorobutyryl Chloride lies in its role as a crucial intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). It is notably employed in the manufacturing of Fexofenadine, an antihistamine, and in the preparation of analogs of Mitomycin C, an antitumor antibiotic. Beyond pharmaceuticals, it finds significant application in the agrochemical industry as a precursor for herbicides and pesticides, contributing to advancements in crop protection. Furthermore, its reactive nature makes it valuable in the polymer sector for modifying polymer chains and synthesizing specialty resins.

Key Considerations When Buying 4-Chlorobutyryl Chloride

For procurement managers and R&D scientists, several factors are crucial when looking to buy 4-Chlorobutyryl Chloride. Firstly, purity is paramount; ensure the product meets the required specifications, often above 99.0%, for sensitive pharmaceutical applications. Secondly, stability of supply is critical for uninterrupted production. Exploring options from established suppliers who maintain robust inventory and production capabilities is advisable.

When considering the price of 4-Chlorobutyryl Chloride, it is essential to evaluate not just the per-unit cost but also the overall value proposition, including quality, consistency, and reliability of the supplier. Manufacturers in China often offer competitive pricing due to economies of scale and efficient production processes, making them attractive partners for businesses worldwide.

Sourcing from China: Advantages and Best Practices

China has emerged as a global hub for chemical manufacturing, offering a wide array of pharmaceutical intermediates and fine chemicals. For 4-Chlorobutyryl Chloride, sourcing from a Chinese manufacturer provides distinct advantages, including cost-effectiveness and access to large-scale production capacities. To ensure a successful procurement, it is recommended to:

  • Verify Supplier Credentials: Look for suppliers with ISO certifications, strong quality control systems, and positive customer testimonials.
  • Request Samples: Always obtain samples for internal testing to confirm purity and suitability for your specific synthesis before placing a bulk order.
  • Understand Lead Times and Shipping: Clarify delivery schedules and shipping terms to align with your project timelines.
  • Inquire About Technical Support: A good supplier will offer technical assistance to help you optimize the use of 4-Chlorobutyryl Chloride in your processes.

By carefully considering these aspects, businesses can confidently purchase 4-Chlorobutyryl Chloride, securing a high-quality intermediate that supports innovation and efficiency in their operations. As your trusted supplier in China, we are committed to providing excellent products and services to meet your chemical needs.