For businesses involved in chemical synthesis and pharmaceutical development, the consistent availability of high-quality raw materials is critical. 4-Fluorocinnamic Acid, identified by its CAS number 459-32-5, is a sought-after intermediate. This guide aims to provide valuable perspectives for procurement managers and R&D scientists on how to effectively buy this compound, emphasizing insights from manufacturers and suppliers, particularly those in China.

Understanding the Value of 4-Fluorocinnamic Acid

4-Fluorocinnamic Acid is a fluorinated derivative of cinnamic acid, presenting as a white to light yellow crystalline powder. Its chemical formula is C9H7FO2, with a molecular weight of 166.15. The compound's significance stems from its dual functionality: a carboxylic acid group and an unsaturated carbon-carbon double bond, alongside a fluorine atom on the aromatic ring. This combination makes it an exceptionally useful synthon in organic chemistry. In the pharmaceutical sector, it is employed as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs), where the fluorine atom can impart desirable properties like enhanced metabolic stability and lipophilicity. Researchers also utilize it in the creation of novel materials and complex organic molecules.

Manufacturer's Perspective on Quality and Pricing

From a manufacturer's standpoint, producing 4-Fluorocinnamic Acid involves careful control over reaction conditions to ensure high purity, typically above 98%. Common synthesis routes involve reactions such as the Heck reaction or Wittig reaction, starting from precursors like 4-fluorobenzaldehyde. Manufacturers understand that buyers prioritize consistent quality and reliable supply. Therefore, robust quality control measures are implemented throughout the production process. Pricing is influenced by raw material costs, production scale, and purity levels. As a leading manufacturer in China, we are committed to offering competitive prices for 4-Fluorocinnamic Acid without compromising on quality. Buyers looking to purchase this chemical should inquire about current market prices and explore bulk discounts.

Supply Chain Management and Procurement Best Practices

Effective procurement of 4-Fluorocinnamic Acid involves more than just finding the lowest price. Key considerations for buyers include:

  • Supplier Reliability: Partnering with established manufacturers ensures consistent product availability and adherence to specifications. Verify supplier credentials and production capacity.
  • Purity Standards: For pharmaceutical applications, ≥98% or even ≥99.5% purity is often required. Always request a Certificate of Analysis (CoA) for each batch.
  • Packaging and Delivery: Ensure the supplier offers appropriate packaging for your needs (e.g., 5g, 25g, bulk) and can meet your delivery timelines.
  • Technical Support: Good manufacturers provide comprehensive technical data sheets and are available to answer queries regarding product handling and application.
  • Sample Testing: Requesting a free sample before placing a large order is a prudent step to validate product quality and suitability for your specific processes.

Conclusion

For professionals seeking to buy 4-Fluorocinnamic Acid (CAS 459-32-5), understanding the manufacturer's role in ensuring quality and competitive pricing is crucial. By focusing on purity, supply chain stability, and excellent customer service, buyers can secure a reliable source for this vital chemical intermediate. Engaging with reputable Chinese manufacturers offers an excellent opportunity to obtain high-grade 4-Fluorocinnamic Acid at favorable terms. Reach out to us to request a quote and explore how we can support your chemical procurement needs.