In the competitive landscape of pharmaceutical manufacturing and research, the procurement of essential intermediates like 4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 13721-01-2) requires careful consideration of several factors: price, purity, and supplier reliability. This article aims to guide procurement managers and R&D scientists through the process of effectively sourcing this critical compound. If you are looking to buy 4-oxo-1,4-dihydroquinoline-3-carboxylic acid, understanding these elements will help you secure the best value and quality.

Understanding Pricing and Quality Standards

The price of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid can vary based on purity, quantity, and the supplier's origin. As a high-purity pharmaceutical intermediate, it typically commands a premium. When requesting a quote, always inquire about the purity levels, usually expressed as a percentage (e.g., ≥99.0% by HPLC). Higher purity often correlates with a higher price but is essential for downstream synthesis to avoid introducing impurities that could affect the final drug product.

The Importance of Supplier Reliability

Reliability is a cornerstone of any successful supply chain. When selecting a CAS 13721-01-2 supplier, evaluate their track record, certifications, and ability to consistently deliver. A reputable manufacturer will:

  • Provide comprehensive Certificates of Analysis (COA) for each batch.
  • Have established quality management systems (e.g., ISO certifications).
  • Offer clear communication and responsive customer service.
  • Ensure timely delivery to meet your production schedules.

Choosing a reliable manufacturer in China can offer significant cost advantages and access to advanced chemical synthesis capabilities, provided they meet stringent international quality benchmarks.

Applications Driving Demand

The demand for 4-oxo-1,4-dihydroquinoline-3-carboxylic acid is largely driven by its indispensable role in the synthesis of crucial pharmaceuticals, particularly HIV-1 integrase inhibitors. Its consistent quality is paramount for ensuring the therapeutic efficacy of these life-saving drugs. Furthermore, its versatility as a quinoline building block makes it valuable for broader drug discovery initiatives.

In summary, when you decide to purchase 4-oxo-1,4-dihydroquinoline-3-carboxylic acid, prioritize suppliers who offer a balance of competitive pricing, guaranteed high purity, and exceptional reliability. A strategic partnership with a trusted pharmaceutical intermediate supplier is vital for the success of your R&D and manufacturing operations.