For chemists and procurement specialists in the pharmaceutical sector, identifying high-quality raw materials is a cornerstone of successful drug development and manufacturing. 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline, known by its CAS number 74852-62-3, is a critical intermediate, particularly in the synthesis of antifungal agents like Itraconazole. This article focuses on what buyers should look for when they intend to purchase this compound, emphasizing quality assurance and reliable sourcing from China.

Defining Quality for CAS 74852-62-3

The efficacy of downstream pharmaceutical products directly depends on the quality of their precursor materials. When sourcing 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline, key quality indicators include:

  • Purity: Look for a stated purity of 95% or higher, ideally verified by High-Performance Liquid Chromatography (HPLC). This ensures minimal impurities that could complicate synthesis or compromise the final drug's profile.
  • Appearance: The compound typically appears as a Dark Purple to Dark Grey Solid. Any significant deviation from this description should prompt further investigation.
  • Melting Point: A melting point around 186°C is a standard indicator of purity. Variations might suggest impurities or improper storage.
  • Stability and Storage: The material should be stable under normal temperature and pressure. Suppliers often recommend storage in an inert atmosphere and in a dark place to maintain its integrity.
  • Chemical Identity: Confirming the correct CAS number (74852-62-3) and molecular formula (C17H21N3O) is fundamental.

Reliable Sourcing from Chinese Manufacturers

China is a significant global supplier of pharmaceutical intermediates, and 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline is readily available from numerous reputable manufacturers. When selecting a supplier, consider the following:

  • Documentation: Always request a Certificate of Analysis (CoA) for each batch, detailing purity, testing methods, and relevant physical properties. Safety Data Sheets (SDS) are also crucial for safe handling.
  • Bulk Purchase Capabilities: If your needs are for large-scale production, verify the manufacturer's capacity and lead times. Establish a reliable supply chain to prevent production delays.
  • Competitive Pricing: Obtain quotes from multiple suppliers to ensure you are getting the best market price for your required quantity and quality. Direct inquiry with manufacturers often yields the most competitive rates.
  • Customer Service: Responsive communication and technical support are indicators of a trustworthy supplier.

Why Choose a Verified Supplier?

For researchers and pharmaceutical developers, engaging with a verified supplier of 4-[4-(4-methoxyphenyl)piperazin-1-yl]aniline means gaining access to a consistent, high-quality intermediate. This chemical is essential for producing effective antifungal treatments, and its reliable procurement directly impacts project timelines and product quality. If you are looking to buy this crucial compound, leveraging the expertise of established chemical companies in China will ensure your sourcing needs are met efficiently and effectively.