Procurement managers and R&D scientists in the chemical and pharmaceutical industries frequently encounter specialized intermediates that drive innovation. 2-Amino-5-fluorobenzonitrile, identified by its CAS number 61272-77-3, is one such compound, recognized for its utility across various sectors. This article provides a detailed look at its key properties and diverse applications, guiding those looking to buy or source this valuable intermediate.

Chemically, 2-Amino-5-fluorobenzonitrile is a fluorinated aromatic compound characterized by an amine group and a nitrile group attached to a benzene ring, with a fluorine atom positioned at the 5-position relative to the amine. Its molecular formula is C7H5FN2, and it possesses a molecular weight of approximately 136.13 g/mol. Typically, it presents as a light yellow crystalline powder, with a reported melting point in the range of 92-96°C. This form factor makes it amenable to standard chemical handling and processing.

The applications of 2-Amino-5-fluorobenzonitrile are broad and significant. In pharmaceutical synthesis, it serves as a critical building block for creating complex molecular structures, particularly for drugs targeting neurological conditions, bacterial infections, and as kinase inhibitors in oncology. Its electron-deficient aromatic ring and the reactivity of its functional groups facilitate the formation of heterocyclic systems essential for API development. For agrochemical applications, it functions as an intermediate in the synthesis of crop protection agents, contributing to enhanced efficacy and stability.

Beyond these primary uses, its unique properties also lend themselves to materials science, where it can be incorporated into the synthesis of fluorescent dyes and organic electronic materials. For buyers seeking this compound, understanding its reactivity and purity is crucial. Manufacturers often guarantee purity levels of 98% or higher via HPLC. When considering a purchase, requesting detailed specifications, safety data, and competitive pricing from suppliers, particularly those in China known for fine chemical manufacturing, is a standard business practice. Securing a reliable source for high-quality 2-Amino-5-fluorobenzonitrile (CAS 61272-77-3) is key to advancing research and development projects.