For procurement managers and R&D scientists in the pharmaceutical industry, sourcing reliable, high-purity intermediates is paramount. One such crucial compound is 2-Amino-5-fluorobenzonitrile, identified by its CAS number 61272-77-3. This fluorinated aromatic intermediate plays a pivotal role in the synthesis of a wide range of active pharmaceutical ingredients (APIs), particularly those targeting complex diseases.

As a key building block, 2-Amino-5-fluorobenzonitrile is instrumental in constructing fused heterocyclic systems. These structures are frequently found in drug candidates such as kinase inhibitors, which are vital in cancer therapy, and also in agents designed to treat neurological disorders and bacterial infections. Its unique chemical structure, featuring an amine and a nitrile group ortho to each other on a fluorinated benzene ring, facilitates efficient cyclization reactions. Furthermore, the presence of fluorine can enhance a molecule's metabolic stability and its ability to penetrate biological membranes, both critical attributes for effective pharmaceuticals.

When considering the purchase of 2-Amino-5-fluorobenzonitrile, understanding its specifications and sourcing from reputable manufacturers is key. Buyers often look for high purity levels, typically above 98% or 99%, to ensure the integrity and efficacy of the final drug product. The physical form, usually a light yellow crystalline powder, is also a standard characteristic. As a buyer in the B2B space, you will want to partner with a supplier who can guarantee consistent quality, reliable supply chain management, and competitive pricing. Exploring options from manufacturers in China can offer significant cost advantages without compromising on quality, especially when looking to buy in bulk.

The process of procuring this essential intermediate often involves requesting quotes and samples. Detailed technical data sheets (TDS), Certificates of Analysis (CoA), and Material Safety Data Sheets (MSDS) are standard requirements for due diligence. By establishing a relationship with a trusted manufacturer or supplier of 2-Amino-5-fluorobenzonitrile (CAS 61272-77-3), pharmaceutical companies can secure a vital component for their drug development pipeline, ensuring timely progress and the creation of innovative therapies.