For professionals in the chemical industry, a thorough understanding of chemical properties and safe handling practices is paramount. Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate (CAS 782501-25-1) is a specialized chemical intermediate used in various synthetic processes. This article provides essential insights into its properties, potential applications, and critical handling considerations, aimed at procurement managers and research scientists seeking reliable information from a knowledgeable manufacturer.

Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate, with the molecular formula C₁₀H₁₈ClNO₄S and a molecular weight of 283.77 g/mol, is characterized by its typical appearance as a white to off-white powder or crystalline powder. This physical form is common for many organic intermediates. Key predicted properties include a high boiling point of approximately 369.5±31.0 °C and a density of around 1.30±0.1 g/cm³. These properties are important for process engineers designing reaction and purification steps. When you purchase this compound, understanding these parameters assists in efficient process design and material management.

From a safety perspective, the sulfonyl chloride group indicates reactivity, particularly with moisture. Therefore, Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate should be stored under an inert atmosphere, such as nitrogen or argon, at refrigeration temperatures (2-8°C) to maintain its stability and prevent degradation. Exposure to water can lead to hydrolysis, potentially releasing corrosive substances. Safety data sheets (SDS) from reliable suppliers will detail specific hazard statements, such as H314 (Causes severe skin burns and eye damage), and precautionary statements (P-statements) guiding safe handling. As a professional supplier, we emphasize adherence to these safety protocols for all our clients.

The compound's pKa of -3.72±0.40 suggests it is a relatively strong acid. This reactivity profile makes it a valuable tool in organic synthesis, but also necessitates careful handling and storage. Users often search for ‘CAS 782501-25-1 price’ or ‘buy Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate’ to procure this intermediate for specific applications, ranging from pharmaceutical research to the synthesis of fine chemicals. Accessing this compound from a reputable manufacturer in China ensures that you receive a product that meets the required purity standards, typically 97% or higher.

In conclusion, Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate is a potent intermediate with well-defined properties. Adhering to recommended storage and handling procedures, as provided by trusted manufacturers and suppliers, is crucial for maintaining product integrity and ensuring workplace safety. By partnering with experienced providers, researchers and manufacturers can effectively incorporate this chemical into their synthetic strategies.