For any procurement manager or R&D scientist involved in chemical synthesis, a thorough understanding of a compound's properties is fundamental. N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide (CAS 90357-53-2) is no exception. This specialized chemical intermediate possesses a unique set of physical and chemical characteristics that dictate its handling, storage, and application in various synthesis pathways. As a leading manufacturer and supplier, we aim to provide clarity on these essential aspects.

Physically, N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide is typically described as a White to Off-White Powder or crystalline solid. This form factor is common for many organic intermediates of its molecular weight and complexity. The solid state facilitates easier handling, weighing, and storage compared to liquids or gases, which is a practical advantage for laboratory and industrial use. Its appearance is a primary indicator of purity, and reputable manufacturers will ensure consistency in this aspect.

Chemically, the molecule's properties are defined by its functional groups. The presence of the trifluoromethyl (CF3) group often imparts increased lipophilicity and metabolic stability to molecules derived from it. The cyano (CN) group is an electron-withdrawing group that can influence the reactivity of the aromatic ring and can also be a site for further chemical transformations. The methacrylamide moiety, with its vinyl group and amide linkage, is particularly important. The double bond in the methacrylamide group makes it susceptible to polymerization, hence its designation as a monomer, but also allows it to participate in addition reactions. The amide linkage itself provides a degree of rigidity and polarity.

Key chemical properties often noted include its molecular weight, which is approximately 254.21 g/mol, and its molecular formula, C12H9F3N2O. Information regarding its melting point is also crucial for assessing purity and stability; it is typically reported in the range of 137-139 °C or slightly higher, around 143 °C, depending on the source and purity. Its solubility in common organic solvents like acetonitrile and chloroform is generally described as slight, indicating that careful solvent selection may be necessary for reactions and purification.

Safety information is also critical. It is classified under UN3077 with Hazard Class 9 and Packing Group III, suggesting it is an environmentally hazardous substance. Proper handling procedures, including the use of personal protective equipment (PPE) and appropriate ventilation, are necessary. Storage at temperatures between 2-8°C is often recommended to maintain its stability, especially given its potential sensitivity to light and its propensity for polymerization under certain conditions.

For professionals looking to buy N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide, understanding these properties is vital for effective research and procurement. We, as a dedicated manufacturer and supplier, provide detailed technical data to support your endeavors. Our commitment is to offer this crucial intermediate with consistent quality and reliable specifications, ensuring your synthetic projects proceed smoothly.