For scientists, researchers, and procurement specialists in the chemical and pharmaceutical industries, a thorough understanding of a compound's properties and applications is fundamental. (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol, identified by CAS number 330156-50-8, is a specialized organic molecule whose precise characteristics make it invaluable for specific synthetic pathways, most notably in the pharmaceutical sector.

Physically, (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is typically described as a light yellow solid. Its melting point range is usually between 41.0 to 45.0 °C, indicating it exists as a solid under standard room temperatures. Key chemical properties include its molecular formula C8H7Cl2FO and a molecular weight of approximately 209.045 g/mol. The presence of chlorine and fluorine atoms on the phenyl ring, along with a chiral hydroxyl group, imparts specific reactivity and stereochemical characteristics that are crucial for its intended uses.

The primary and most significant application of (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is its role as a key pharmaceutical intermediate. It is critically used in the synthesis of Crizotinib (CAS 877399-52-5), a targeted therapy drug used to treat certain types of non-small cell lung cancer. The specific (R) stereochemistry of this alcohol is essential for Crizotinib's biological activity, highlighting the importance of enantiomeric purity in its production.

Beyond its direct use in Crizotinib synthesis, this chiral alcohol can serve as a versatile building block in broader organic synthesis. Its structure allows for various chemical transformations, enabling chemists to construct complex molecules with defined stereocenters. Researchers exploring new drug candidates or developing novel chemical entities might leverage this compound's unique attributes. When sourcing this chemical, buyers should look for suppliers who can guarantee a purity of at least 98.0%, with a particular emphasis on enantiomeric purity, which is often a key specification for pharmaceutical intermediates.

The synthesis of (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is often achieved through asymmetric reduction techniques, ensuring the correct enantiomer is formed with high selectivity. Manufacturers specializing in chiral chemistry play a vital role in making this compound available in the quantities and purities required by the pharmaceutical industry. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to providing such high-value intermediates, backed by robust quality control and technical expertise, ensuring that researchers and manufacturers can confidently buy and utilize this compound for their critical applications.

In summary, (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is a well-characterized chiral alcohol with critical applications in pharmaceutical synthesis, particularly for targeted cancer therapies. Its specific physical and chemical properties, combined with stringent purity requirements, underscore its importance as an advanced chemical intermediate available from specialized manufacturers.