For procurement professionals and research chemists, understanding the market dynamics, particularly pricing and purity standards, is crucial when acquiring chemical intermediates. 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine (CAS: 90213-66-4) is no exception. As a vital component in the synthesis of pharmaceuticals like Tofacitinib, its cost and quality directly influence project budgets and outcomes. This article provides insights into the factors affecting the price of this compound and what purity levels to look for when you need to buy.

Factors Influencing the Price of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

The price of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine can vary significantly based on several factors:

  • Purity Level: Higher purity grades (e.g., ≥99%) command higher prices than lower grades due to the more rigorous purification processes involved. For pharmaceutical synthesis, high purity is typically non-negotiable.
  • Order Volume: Bulk purchases generally offer a lower per-unit cost compared to small R&D quantities. Manufacturers often provide tiered pricing based on order size.
  • Supplier Type: Prices can differ between direct manufacturers, distributors, and traders. Direct manufacturers often offer the most competitive pricing.
  • Raw Material Costs: Fluctuations in the cost of precursor chemicals used in the synthesis of 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine can impact its final price.
  • Geographical Origin: While this article focuses on sourcing from China, prices can vary based on the supplier's location and associated logistical costs.
  • Market Demand: High demand, particularly for applications like Tofacitinib production, can influence pricing.

Ensuring Optimal Purity for Your Needs

When you buy 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine, always scrutinize the Certificate of Analysis (CoA). For most pharmaceutical applications, purity of ≥99% by HPLC is standard. Impurity profiles are also critical; even small amounts of specific impurities can derail complex synthesis routes or compromise the safety and efficacy of the final drug product. Always verify that the supplier provides detailed impurity data and that these fall within acceptable limits.

For researchers and procurement managers looking to purchase this essential pharmaceutical intermediate, comparing quotes from multiple reliable suppliers is a sound strategy. Understanding the interplay between price and purity will help you make informed decisions, ensuring you obtain a high-quality product at a competitive price. Connecting with manufacturers in China provides a strong avenue for securing this crucial compound for your synthesis projects.