PVP/VA 64: A Safe and Effective Excipient for Pharmaceutical and Nutritional Applications
At NINGBO INNO PHARMCHEM CO.,LTD., we prioritize the safety and efficacy of the excipients we supply. The PVP/VA 64 copolymer, also known as Copovidone, stands out for its excellent safety profile, making it a preferred choice for pharmaceutical formulations and even nutritional supplements.
The established safety of PVP/VA 64 is underscored by its GRAS (Generally Recognized As Safe) status, affirmed by the U.S. Food and Drug Administration (FDA). This designation allows for its use in food and nutritional products, reflecting a high level of confidence in its non-toxicity when consumed appropriately.
Extensive toxicological studies have further validated the safety of this copovidone pharmaceutical excipient. Non-clinical studies conducted on animal models, including rats and dogs, have demonstrated the absence of significant adverse effects even at high dietary levels. These studies have established high no-observed-adverse-effect levels (NOAELs), indicating a wide margin of safety for typical exposures. Furthermore, PVP/VA 64 has shown no irritating or sensitizing effects on the skin, making it suitable for applications with direct contact.
The PVP VA 64 copolymer binder function in pharmaceutical tablets is well-supported by its safety profile. Its use as a dry binder for direct compression, film former, and matrix former for solid dispersions is therefore well-justified from a safety perspective. The vinylpyrrolidone vinyl acetate copolymer uses in pharmaceuticals are safe and effective when manufactured to industry standards.
When formulators choose to buy PVP/VA 64 from NINGBO INNO PHARMCHEM CO.,LTD., they are selecting an excipient with a robust safety dossier. This allows for the development of high-quality, safe, and effective pharmaceutical products and supplements, ensuring consumer well-being and regulatory compliance. The commitment to quality and safety ensures that our PVP/VA 64 continues to meet the stringent requirements of the global health and wellness market.
Perspectives & Insights
Agile Reader One
“These studies have established high no-observed-adverse-effect levels (NOAELs), indicating a wide margin of safety for typical exposures.”
Logic Vision Labs
“Furthermore, PVP/VA 64 has shown no irritating or sensitizing effects on the skin, making it suitable for applications with direct contact.”
Molecule Origin 88
“The PVP VA 64 copolymer binder function in pharmaceutical tablets is well-supported by its safety profile.”