High-Quality Copovidone PVP/VA 64: Your Ultimate Binder and Film-Former
Discover the versatility of PVP/VA 64, the advanced copolymer essential for pharmaceutical and cosmetic innovation.
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PVP/VA 64 Copolymer
Copovidone, also known as PVP/VA 64, is a high-performance copolymer of N-vinylpyrrolidone and vinyl acetate, widely recognized for its exceptional properties as a tablet binder and film-forming agent in the pharmaceutical and cosmetic industries.
- As a leading copovidone pharmaceutical excipient, PVP/VA 64 serves as an excellent dry binder for direct compression, significantly enhancing tablet hardness and reducing friability.
- Leveraging its properties as a film former, this vinylpyrrolidone vinyl acetate copolymer finds extensive use in cosmetic formulations and pharmaceutical coatings, ensuring stability and efficacy.
- The copolymer's potential as a matrix former for solid dispersions makes it invaluable for improving the solubility of poorly soluble drug actives when used in hot melt extrusion processes.
- Its safety profile, including US FDA GRAS status, underscores its suitability for a wide range of applications, from pharmaceuticals to nutritional supplements.
Key Advantages of Using PVP/VA 64 Copolymer
Enhanced Tablet Binding
Utilizing the PVP/VA 64 copolymer for direct compression applications ensures superior tablet binding, making it a preferred choice for formulations prone to capping, thanks to its inherent plasticity.
Superior Film Formation
As a versatile film former, the vinylpyrrolidone vinyl acetate copolymer creates stable, flexible films suitable for pharmaceutical coatings and cosmetic applications, offering excellent adhesion.
Advanced Dispersion Technology
The copolymer's capability as a matrix former for amorphous solid dispersions enhances drug solubility, a critical factor in hot melt extrusion and achieving desired bioavailability.
Key Applications
Pharmaceutical Tablets
PVP/VA 64 copolymer is a top-tier dry binder for direct compression and wet granulation, providing excellent compressibility and adhesion for robust tablet formulations.
Cosmetic Formulations
In cosmetics, it functions as an effective film former and styling agent, contributing to the performance of hair gels, sprays, and lotions.
Solid Dispersions
As a matrix former for solid dispersions via hot melt extrusion, it aids in the solubilization of challenging active pharmaceutical ingredients, improving their therapeutic effectiveness.
Hair Styling Products
Its film-forming and fixative properties make it an essential ingredient in hair styling products, providing hold and curl retention even in high humidity.