The Role of 1-(3-Amino-2-hydroxyphenyl)ethanone in API Synthesis
The synthesis of Active Pharmaceutical Ingredients (APIs) is a cornerstone of the pharmaceutical industry, relying heavily on a precise sequence of chemical reactions involving various intermediates. 1-(3-Amino-2-hydroxyphenyl)ethanone, bearing the CAS number 70977-72-9, plays a pivotal role as one such intermediate. Its chemical structure, characterized by an aromatic ring with hydroxyl, amino, and acetyl substituents, makes it a versatile building block for creating complex drug molecules.
One of the most significant applications of 1-(3-Amino-2-hydroxyphenyl)ethanone is in the synthesis pathway of ranlukast. Ranlukast is a potent leukotriene receptor antagonist, a class of drugs used to treat inflammatory conditions such as asthma and allergic rhinitis. The efficacy and safety of ranlukast are directly linked to the purity and consistent quality of the intermediates used in its production, underscoring the importance of sourcing high-grade 1-(3-Amino-2-hydroxyphenyl)ethanone.
The production of APIs like ranlukast demands stringent adherence to Good Manufacturing Practices (GMP). This includes meticulous control over reaction parameters, impurity profiling, and comprehensive quality assurance of all raw materials and intermediates. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., a prominent supplier in China, are instrumental in providing pharmaceutical companies with the necessary intermediates that meet these rigorous standards. Their capability in chemical manufacturing ensures that the supply chain remains robust and that the intermediates are consistently available in the required quantities and purity.
Understanding the chemical specifications and potential applications of 1-(3-Amino-2-hydroxyphenyl)ethanone allows researchers and process chemists to optimize synthesis routes, reduce costs, and accelerate the development of new therapies. As a critical component in API synthesis, this intermediate's reliable availability and quality are fundamental to bringing life-saving and life-improving medications to patients worldwide.
One of the most significant applications of 1-(3-Amino-2-hydroxyphenyl)ethanone is in the synthesis pathway of ranlukast. Ranlukast is a potent leukotriene receptor antagonist, a class of drugs used to treat inflammatory conditions such as asthma and allergic rhinitis. The efficacy and safety of ranlukast are directly linked to the purity and consistent quality of the intermediates used in its production, underscoring the importance of sourcing high-grade 1-(3-Amino-2-hydroxyphenyl)ethanone.
The production of APIs like ranlukast demands stringent adherence to Good Manufacturing Practices (GMP). This includes meticulous control over reaction parameters, impurity profiling, and comprehensive quality assurance of all raw materials and intermediates. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., a prominent supplier in China, are instrumental in providing pharmaceutical companies with the necessary intermediates that meet these rigorous standards. Their capability in chemical manufacturing ensures that the supply chain remains robust and that the intermediates are consistently available in the required quantities and purity.
Understanding the chemical specifications and potential applications of 1-(3-Amino-2-hydroxyphenyl)ethanone allows researchers and process chemists to optimize synthesis routes, reduce costs, and accelerate the development of new therapies. As a critical component in API synthesis, this intermediate's reliable availability and quality are fundamental to bringing life-saving and life-improving medications to patients worldwide.
Perspectives & Insights
Bio Analyst 88
“1-(3-Amino-2-hydroxyphenyl)ethanone, bearing the CAS number 70977-72-9, plays a pivotal role as one such intermediate.”
Nano Seeker Pro
“Its chemical structure, characterized by an aromatic ring with hydroxyl, amino, and acetyl substituents, makes it a versatile building block for creating complex drug molecules.”
Data Reader 7
“One of the most significant applications of 1-(3-Amino-2-hydroxyphenyl)ethanone is in the synthesis pathway of ranlukast.”