1-Methyl-3-nitrophthalate, identified by CAS number 21606-04-2, stands as a significant compound within the realm of pharmaceutical intermediates. Its molecular structure, featuring a nitro group and esterified carboxyl groups on a benzene ring, bestows upon it a unique reactivity profile highly valued in organic synthesis. This chemical is not merely a component; it's a critical enabler for the creation of complex molecules essential in modern medicine.

The utility of 1-Methyl-3-nitrophthalate extends to its role as a precursor in the synthesis of various active pharmaceutical ingredients (APIs) and their related impurities. For instance, it plays a part in generating specific impurities associated with Apremilast, a widely used treatment for inflammatory conditions. This application underscores the compound's importance in ensuring the quality and safety of pharmaceuticals through meticulous analytical standard preparation and process control.

As a fine chemical intermediate, its production involves controlled chemical reactions, often starting from related phthalic acid derivatives. Manufacturers in China, such as those specializing in pharmaceutical materials, are key suppliers of this compound, offering it typically with high purity levels, often exceeding 99%. This high purity is non-negotiable for downstream applications where even minute impurities can significantly impact the efficacy or safety profile of the final drug product.

For pharmaceutical scientists and procurement specialists, understanding the chemical properties, such as its crystalline powder form and stability, is vital. When looking to purchase 1-Methyl-3-nitrophthalate, it's crucial to partner with suppliers who can consistently deliver product that meets exact specifications. The competitive pricing offered by many Chinese manufacturers makes it an accessible intermediate for a broad range of research and commercial applications.

In essence, 1-Methyl-3-nitrophthalate is more than just a chemical intermediate; it's a cornerstone for innovation in pharmaceutical development. Its reliable supply and consistent quality from reputable manufacturers empower scientists to push the boundaries of drug discovery and production.