In the competitive landscape of chemical manufacturing, understanding the core attributes of intermediate compounds is crucial for procurement managers and R&D scientists alike. 1-Methyl-3-nitrophthalate, identified by its CAS number 21606-04-2, is a fine chemical intermediate with a specific molecular structure that lends itself to important applications, particularly within the pharmaceutical sector. This article aims to provide a detailed overview of its properties and typical uses.

The chemical name 1-Methyl-3-nitrophthalate precisely describes its structure: a phthalate derivative with a methyl ester at one carboxyl group and a nitro group positioned on the aromatic ring. This arrangement of functional groups imparts specific reactivity, making it a valuable building block for more complex molecules. It is commonly supplied as a white to light yellow crystalline powder, indicating a well-defined solid form suitable for industrial handling and laboratory use. The purity level of this intermediate is typically high, often reported as ≥99%, which is critical for its downstream applications.

The primary application noted for 1-Methyl-3-nitrophthalate is its role as an intermediate in the synthesis of various organic compounds, notably in the pharmaceutical industry. It is recognized for its use in creating specific impurities of pharmaceutical drugs, such as Apremilast. This use highlights its importance not just in drug synthesis but also in the crucial area of pharmaceutical quality assurance and analytical method development. Researchers looking to buy this compound often require it for generating reference standards.

As a chemical reagent, its molecular formula is C9H7NO6 and its molecular weight is approximately 225.16 g/mol. The compound's properties, such as melting point and solubility, are important considerations for synthetic chemists. Manufacturers and suppliers, especially those operating in China, offer this intermediate with a focus on consistent quality and competitive pricing. This makes it an accessible option for companies requiring it for research, development, or small-scale production runs.

For any organization seeking to purchase 1-Methyl-3-nitrophthalate, it is advisable to consult with experienced chemical suppliers who can provide detailed specifications and technical data. Understanding the compound’s properties and application context is key to ensuring successful integration into your chemical processes.