The Role of 2-Cyano-Phenothiazine in Modern Pharmaceutical Synthesis
In the intricate world of pharmaceutical synthesis, certain chemical intermediates stand out due to their indispensable role in creating life-saving and life-enhancing medications. 2-Cyano-Phenothiazine (CAS 38642-74-9) is one such compound, serving as a foundational building block for a range of important pharmaceuticals, most notably antipsychotic drugs.
Chemical Profile of 2-Cyano-Phenothiazine
2-Cyano-Phenothiazine, with the molecular formula C13H8N2S, is characterized by its appearance as a yellow to yellow-green crystalline powder. Its chemical structure features a phenothiazine core with a nitrile group attached at the 2-position. This specific arrangement of atoms grants it unique reactivity, making it a valuable synthon in complex organic chemistry.
The compound's technical specifications are typically detailed by manufacturers and suppliers, often including an assay of 98.5% or higher, with many providing products that test at 99.7% purity. Key physical properties include a melting point usually in the range of 202-203.5°C, underscoring its solid-state nature at room temperature. Understanding these properties is vital for chemists and formulators when integrating it into their synthetic routes.
Primary Application: Synthesis of Pericyazine
The most prominent application of 2-Cyano-Phenothiazine is its use as a key intermediate in the synthesis of pericyazine. Pericyazine is a phenothiazine-class antipsychotic medication used in the treatment of schizophrenia and other psychotic disorders. The phenothiazine nucleus itself is a common structural motif in many psychiatric drugs, and the specific cyano substitution in 2-Cyano-Phenothiazine plays a critical role in the subsequent chemical transformations that lead to the final active pharmaceutical ingredient.
The synthesis pathway involves several steps where 2-Cyano-Phenothiazine acts as a crucial precursor. Researchers and pharmaceutical companies seeking to develop or manufacture pericyazine or related compounds will look for reliable sources that can supply this intermediate in the required quantities and purity levels. As a reputable manufacturer and supplier, we ensure that our 2-Cyano-Phenothiazine meets the stringent requirements for pharmaceutical synthesis.
Beyond Pericyazine: Potential in Research
While its role in pericyazine synthesis is well-established, the chemical structure of 2-Cyano-Phenothiazine also suggests potential utility in other areas of pharmaceutical research and development. As a functionalized phenothiazine derivative, it can be explored as a building block for novel compounds with potential therapeutic activities, perhaps in areas related to neurological disorders, anti-inflammatory agents, or even in materials science due to the inherent properties of the phenothiazine ring system.
For research laboratories and chemical synthesis companies, procuring 2-Cyano-Phenothiazine from a trusted supplier is essential for reproducible and successful outcomes. We pride ourselves on being a reliable source for high-quality pharmaceutical intermediates, supporting innovation in drug discovery and development.
Perspectives & Insights
Core Pioneer 24
“Chemical Profile of 2-Cyano-Phenothiazine2-Cyano-Phenothiazine, with the molecular formula C13H8N2S, is characterized by its appearance as a yellow to yellow-green crystalline powder.”
Silicon Explorer X
“Its chemical structure features a phenothiazine core with a nitrile group attached at the 2-position.”
Quantum Catalyst AI
“This specific arrangement of atoms grants it unique reactivity, making it a valuable synthon in complex organic chemistry.”