For researchers and scientists in the chemical and pharmaceutical sectors, access to high-quality intermediates is the bedrock of innovation. 4-Chloro-2-nitroanisole, designated by CAS number 89-21-4, is one such compound that plays a crucial role in various research and development activities. Its unique chemical structure, featuring a combination of reactive functional groups, makes it an invaluable tool for synthesizing new molecules and exploring novel chemical pathways. Understanding its properties and sourcing effectively is key for any R&D effort.

Chemical Properties and Significance

4-Chloro-2-nitroanisole, with the molecular formula C7H6ClNO3 and a molecular weight of 187.58 g/mol, is typically supplied as a yellow powder. Its melting point, usually in the range of 97-99°C, indicates its stability as a solid. The molecule's core value in R&D stems from its structure:

  • Aromatic Ring: Provides a stable scaffold for further functionalization.
  • Nitro Group (-NO2): Can be readily reduced to an amine (-NH2), a critical step in synthesizing many biologically active compounds and dyes.
  • Chlorine Atom (-Cl): A good leaving group that can be substituted by various nucleophiles, allowing for the introduction of diverse chemical functionalities.
  • Methoxy Group (-OCH3): Modulates the electronic properties of the aromatic ring and can participate in specific reactions.

These features enable 4-Chloro-2-nitroanisole to be used in a wide array of synthetic transformations, making it a critical reagent for chemists exploring new molecular designs.

Applications in Research and Development

The versatility of 4-Chloro-2-nitroanisole makes it a popular choice in chemical R&D for several purposes:

  • Synthesis of Novel Compounds: Researchers utilize it as a starting material to build complex organic molecules with potential applications in pharmaceuticals, materials science, and diagnostics.
  • Medicinal Chemistry: Its derivatives are explored for their biological activities, contributing to the discovery of new therapeutic agents.
  • Methodology Development: It can be used as a model substrate to test new synthetic methodologies or catalytic systems.
  • Fine Chemical Synthesis: Laboratories often require it for the preparation of specific fine chemicals for analytical standards or further research purposes.

When undertaking R&D projects, it is essential to buy 4-Chloro-2-nitroanisole that meets stringent purity requirements. Sourcing from reliable suppliers who can provide Certificates of Analysis (CoA) is crucial to ensure reproducible experimental results.

Effective Sourcing for R&D Labs

For research laboratories, sourcing small to moderate quantities of 4-Chloro-2-nitroanisole is common. It is advisable to identify chemical intermediate suppliers, including those in China, that cater to the R&D market. These suppliers often offer competitive pricing and readily available documentation such as CoA and SDS. Comparing the price for C7H6ClNO3 from different vendors and ensuring timely delivery are key considerations. Many R&D-focused suppliers also offer custom synthesis services, which can be beneficial for specific research needs.

Conclusion

4-Chloro-2-nitroanisole (CAS 89-21-4) is a valuable intermediate that empowers chemical research and development. Its unique structural characteristics and reactivity allow scientists to synthesize a wide range of novel compounds. By prioritizing the sourcing of high-purity material from trustworthy suppliers, researchers can ensure the accuracy and success of their experiments, contributing to advancements in chemistry and related fields.