The pharmaceutical industry relies on a vast array of complex chemical compounds to create life-saving and life-enhancing medications. Among these are crucial intermediates, the building blocks that facilitate the synthesis of active pharmaceutical ingredients (APIs). 4-Chloro-4'-hydroxybenzophenone (CAS 42019-78-3) stands out as a significant intermediate, particularly in the production of widely used lipid-lowering drugs like Fenofibrate. Understanding its role and ensuring a consistent, high-quality supply is vital for pharmaceutical manufacturers.

What is 4-Chloro-4'-hydroxybenzophenone?

Chemically known as (4-chlorophenyl)(4-hydroxyphenyl)methanone, this compound is a derivative of benzophenone. Its structure features a chlorine atom on one phenyl ring and a hydroxyl group on the other, making it a reactive molecule amenable to further chemical transformations. The molecular formula is C13H9ClO2, and its CAS number, 42019-78-3, is universally recognized in chemical databases. As a leading manufacturer of this compound, we ensure its production meets the stringent demands of the pharmaceutical sector.

Key Role in Fenofibrate Synthesis

Fenofibrate is a widely prescribed fibrate drug used to manage hyperlipidemia, specifically high levels of triglycerides and LDL cholesterol, and low levels of HDL cholesterol. The synthesis of Fenofibrate involves several steps, and 4-Chloro-4'-hydroxybenzophenone serves as a pivotal precursor. Its specific chemical structure allows for the subsequent reactions necessary to build the final Fenofibrate molecule. The purity of this intermediate directly impacts the purity and efficacy of the final API, making the selection of a reliable supplier critical.

Why Reliable Sourcing Matters for Pharmaceutical Intermediates

For pharmaceutical companies, the supply chain for critical intermediates like 4-Chloro-4'-hydroxybenzophenone must be robust and dependable.:

  • Quality Consistency: Batch-to-batch consistency in purity and impurity profiles is non-negotiable. Any deviation can lead to production issues, failed batches, or even compromised drug safety.
  • Supply Chain Security: Ensuring uninterrupted access to these materials is essential to avoid production downtime and meet market demand. Relying on a trusted manufacturer mitigates these risks.
  • Regulatory Compliance: Pharmaceutical intermediates must meet strict regulatory standards. Suppliers who provide comprehensive documentation and adhere to Good Manufacturing Practices (GMP) are preferred.

Purchasing Considerations

When looking to buy 4-Chloro-4'-hydroxybenzophenone, pharmaceutical professionals should evaluate potential suppliers based on:

  • Certifications: ISO certifications and adherence to pharmaceutical quality standards.
  • Analytical Data: Comprehensive CoAs and technical data sheets.
  • Production Capacity: Ability to meet required volumes.
  • Logistics: efficient shipping and delivery options.
  • Technical Support: Access to expert advice and support.

Ningbo Inno Pharmchem Co., Ltd. is committed to being your trusted partner in sourcing high-quality 4-Chloro-4'-hydroxybenzophenone. As a dedicated supplier and manufacturer, we ensure that our products meet the demanding standards of the pharmaceutical industry, providing you with the reliability and quality you need to bring essential medicines to market.