In the realm of chemical synthesis, specific compounds serve as linchpins for creating more complex and valuable molecules. 4-Nitro-3-(trifluoromethyl)aniline (CAS: 393-11-3) is one such essential intermediate, critical for advancements in pharmaceuticals and various fine chemical applications. This article is a guide for procurement specialists and research scientists interested in the reliable sourcing and application of this compound.

Chemical Profile and Properties

4-Nitro-3-(trifluoromethyl)aniline is typically supplied as a powder with a purity of 97%. Its chemical identity is defined by the molecular formula C7H5F3N2O2 and a molecular weight of 206.12 g/mol. The molecule's structure features an aniline core substituted with a nitro group and a trifluoromethyl group. This combination makes it highly reactive and useful in a variety of synthetic transformations. Key physical characteristics, such as a melting point of 125-129 °C, and its solubility behavior in common organic solvents, are vital data for chemists. As a known metabolite of Flutamide, an important pharmaceutical, its consistent quality and availability are of paramount importance for drug manufacturers.

Applications: From Pharmaceuticals to Advanced Materials

The primary application of 4-Nitro-3-(trifluoromethyl)aniline is as a pharmaceutical intermediate, particularly in the synthesis of anti-cancer drugs like Flutamide. The incorporation of fluorinated groups, such as the trifluoromethyl moiety, often imparts desirable properties to drug molecules, including enhanced bioavailability and metabolic stability. This makes intermediates like 4-Nitro-3-(trifluoromethyl)aniline highly valuable in drug discovery and development. Beyond the pharmaceutical sector, this compound is also a versatile tool in general organic synthesis, enabling the creation of novel agrochemicals, dyes, and specialty materials. For any of these applications, the ability to buy 4-Nitro-3-(trifluoromethyl)aniline from a trusted manufacturer is key.

Effective Sourcing and Supplier Selection

For chemical buyers, securing a reliable supply of 4-Nitro-3-(trifluoromethyl)aniline involves a diligent approach to sourcing. Key considerations include:

  • Quality Standards: Always prioritize suppliers who can provide comprehensive Certificates of Analysis detailing product purity and specifications.
  • Manufacturing Excellence: Partner with manufacturers that have robust quality control systems and a proven track record in producing high-purity chemical intermediates.
  • Competitive Pricing and Bulk Availability: Investigate the 4-Nitro-3-(trifluoromethyl)aniline price from various suppliers, especially those in China, to ensure cost-effectiveness for both small and large-scale orders.
  • Supply Chain Reliability: Confirm that your chosen manufacturer can guarantee a consistent and timely supply to avoid disruptions in your production or research timelines.

NINGBO INNO PHARMCHEM CO.,LTD. is a leading chemical manufacturer and supplier committed to delivering high-quality intermediates. We offer reliable sourcing for 4-Nitro-3-(trifluoromethyl)aniline and invite all interested R&D scientists and procurement managers to contact us for a competitive quote and to discuss their specific requirements. Our expertise ensures you receive the quality and service you need.