Cardiovascular health is a global priority, driving continuous innovation and demand for effective treatments. Within the pharmaceutical industry, the synthesis of crucial cardiovascular drugs relies heavily on the availability of high-quality intermediates. One such vital compound is 4-Phenylbutan-2-amine (CAS: 22374-89-6), a key precursor in the production of Labetalol, a widely prescribed antihypertensive medication. This article delves into the role of 4-Phenylbutan-2-amine for R&D scientists and procurement managers involved in cardiovascular drug development and manufacturing.

Understanding the Chemical Foundation:

4-Phenylbutan-2-amine is an organic amine with a specific molecular structure that makes it indispensable for building the Labetalol molecule. Its chemical properties, including its physical state as a colorless liquid and its high purity (typically ≥99.0% assay), are critical for ensuring the success of complex multi-step organic syntheses. For R&D scientists, working with a well-characterized and consistently pure intermediate like 4-Phenylbutan-2-amine allows for more predictable reaction outcomes and efficient optimization of synthetic routes.

Labetalol: A Dual-Action Antihypertensive:

Labetalol is a unique drug that combines alpha and beta-adrenergic blocking properties, making it highly effective in managing hypertension, including hypertensive emergencies. The precise stereochemistry and functional groups derived from 4-Phenylbutan-2-amine are essential for Labetalol's therapeutic activity. Therefore, securing a reliable supply of this intermediate is fundamental for manufacturers aiming to produce high-quality Labetalol.

Procurement Strategies for Pharmaceutical Intermediates:

Procurement managers seeking to buy 4-Phenylbutan-2-amine must prioritize suppliers who demonstrate a strong commitment to quality and supply chain reliability. Factors to consider include:

  • Supplier Reputation: Partnering with established manufacturers with a proven track record in pharmaceutical intermediates.
  • Quality Control: Verification of purity assays, impurity profiles, and adherence to specifications.
  • Manufacturing Capacity: Ensuring the supplier can meet both current and future demand.
  • Global Reach: Experience in international logistics and regulatory compliance.

As a leading manufacturer and supplier of 4-Phenylbutan-2-amine in China, NINGBO INNO PHARMCHEM CO.,LTD. understands the critical nature of these intermediates. We are dedicated to providing R&D scientists and procurement professionals with a product that meets the highest standards, ensuring the efficient and safe production of cardiovascular drugs like Labetalol. Contact us to discuss your requirements and secure a dependable source for this vital pharmaceutical intermediate.