For Active Pharmaceutical Ingredient (API) manufacturers, the selection of raw materials and intermediates is a foundational step that dictates the success of their entire production process. Among the vast array of necessary chemical building blocks, 4-Phenylbutan-2-amine (CAS: 22374-89-6) stands out as a critical intermediate, particularly for the synthesis of Labetalol, a vital medication for managing hypertension. This article highlights the significance of 4-Phenylbutan-2-amine for API manufacturers and the advantages of sourcing it from reputable Chinese suppliers.

The Crucial Role of 4-Phenylbutan-2-amine:

4-Phenylbutan-2-amine serves as a direct precursor in the complex synthesis pathway leading to Labetalol. Its specific chemical structure and, more importantly, its purity, directly impact the efficiency and quality of the final API. API manufacturers must ensure that the 4-Phenylbutan-2-amine they procure meets stringent specifications, including:

  • High Assay: Typically, a purity level of ≥99.0% is required, validated by analytical techniques such as GC and titration. This minimizes the introduction of impurities into the API.
  • Controlled Impurity Profile: Manufacturers need to be confident that the intermediate contains minimal levels of unwanted byproducts, which could complicate downstream processing or affect API safety.
  • Physical Consistency: The compound's state as a colorless liquid and its consistent physical properties are essential for predictable handling and reaction kinetics in large-scale manufacturing.

Why Choose a Chinese Manufacturer?

The global landscape of pharmaceutical intermediate supply is significantly shaped by Chinese manufacturers. For API manufacturers looking to buy 4-Phenylbutan-2-amine, China offers several compelling advantages:

  • Economies of Scale: Chinese chemical plants are equipped for large-volume production, ensuring a stable supply for global pharmaceutical operations.
  • Competitive Pricing: Efficient manufacturing processes and a robust supply chain often translate to more competitive pricing for intermediates.
  • Technical Expertise: Many Chinese chemical companies possess deep expertise in organic synthesis and quality control, making them reliable partners for complex intermediates.

NINGBO INNO PHARMCHEM CO.,LTD. is a premier manufacturer and supplier of 4-Phenylbutan-2-amine, dedicated to supporting API manufacturers. We understand the critical importance of quality and consistency in your production processes. By partnering with us, you gain access to a reliable source of high-purity 4-Phenylbutan-2-amine, ensuring your Labetalol production is both efficient and compliant. Contact us to secure your supply and discuss how we can meet your specific needs.