Homopiperazine (CAS 505-66-8), a seven-membered heterocyclic diamine, stands as a cornerstone in modern pharmaceutical synthesis. Its unique structural attributes and chemical reactivity make it an indispensable building block for a wide range of therapeutic agents. Understanding its properties and synthesis is key for R&D scientists and formulation chemists looking to leverage its potential. As a leading pharmaceutical intermediate supplier, we delve into the chemical significance of Homopiperazine.

Chemically, Homopiperazine possesses the molecular formula C5H12N2, with a molecular weight of 100.16. Its structure features a seven-membered ring containing two nitrogen atoms, allowing for diverse derivatization. This makes it an ideal starting material for creating complex molecules with specific biological activities. Its melting point typically ranges from 38-40°C, and it appears as a white to light yellow crystalline mass. Importantly, Homopiperazine is known to be air-sensitive and hygroscopic, necessitating careful handling and storage conditions, which manufacturers like us meticulously manage.

The synthesis of Homopiperazine often involves multi-step processes. One common route utilizes ethylenediamine as a primary raw material, undergoing reactions such as sulfonylation, cyclization, and de-sulfonylation. Alternative pathways employ other amino compounds, showcasing the flexibility in its production. The availability of cost-effective raw materials and optimized reaction conditions are critical for efficient industrial-scale manufacturing, ensuring a reliable supply for pharmaceutical companies. We, as a dedicated manufacturer, continuously refine these processes.

The true value of Homopiperazine shines in its applications within pharmaceutical development. It is a crucial intermediate in the synthesis of drugs such as fasudil hydrochloride, used for cardiovascular conditions, and in the preparation of potent H3 receptor antagonists, which are investigated for neurodegenerative diseases like Alzheimer's. Furthermore, derivatives have demonstrated sedative, anti-psychotic, anti-inflammatory, and anti-neurotic properties. This broad therapeutic applicability underscores why Homopiperazine is a sought-after compound for pharmaceutical R&D.

For research chemists aiming to buy Homopiperazine for novel drug discovery, partnering with a reputable manufacturer is paramount. Access to detailed technical specifications, consistent purity, and responsive customer support are indicative of a reliable supplier. We pride ourselves on providing comprehensive technical data and supporting our clients in their drug development endeavors, ensuring they receive a high-quality product that facilitates their research.

In summary, Homopiperazine's chemical structure, synthesis routes, and extensive applications in pharmaceutical development solidify its position as a vital intermediate. Its role in creating life-saving and life-improving medications makes it an essential component in the chemical industry. For those seeking to purchase this key building block, engaging with experienced Homopiperazine suppliers is the first step towards successful innovation.