The incorporation of non-canonical amino acids has become a powerful strategy in modern biochemistry and pharmaceutical development, offering ways to imbue peptides and proteins with novel properties. Among these, amino acids functionalized with halogens, particularly iodine, present unique opportunities. NINGBO INNO PHARMCHEM CO.,LTD. highlights the significance of Boc-β-iodo-Ala-OMe as a prime example of such a valuable synthetic tool.

Boc-β-iodo-Ala-OMe (CAS 93267-04-0) is an N-protected amino acid methyl ester featuring an iodine atom at the beta-carbon. The iodine atom in this position is particularly advantageous for several reasons. Firstly, it acts as an excellent leaving group in nucleophilic substitution reactions, allowing for the straightforward introduction of various nucleophiles. This is fundamental for synthesizing a wide array of modified amino acids that are not readily available from natural sources.

Secondly, the carbon-iodine bond is amenable to transition metal-catalyzed cross-coupling reactions, such as palladium-catalyzed couplings. This capability enables chemists to attach complex organic fragments or biomolecules to the amino acid scaffold, opening up pathways for creating highly functionalized peptides, peptidomimetics, or even small molecule drugs. The ability to buy Boc-β-iodo-Ala-OMe for these advanced synthetic transformations is crucial for cutting-edge research.

The N-Boc protecting group on the alpha-amino nitrogen ensures that the molecule can be selectively incorporated into peptide chains using standard solid-phase or solution-phase peptide synthesis techniques. Its removal under mild acidic conditions then reveals the free amine for subsequent coupling steps.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing the scientific community with high-quality chemical intermediates. Our Boc-β-iodo-Ala-OMe is manufactured with stringent quality control measures to ensure purity and consistent performance. We serve as a reliable manufacturer and supplier for researchers in China and internationally, offering competitive pricing for bulk purchases. We encourage all those seeking to advance their projects with iodine-containing amino acids to request a quote or sample from us.

By partnering with NINGBO INNO PHARMCHEM CO.,LTD., you gain access to essential building blocks like Boc-β-iodo-Ala-OMe, supported by our expertise and dedication to scientific progress.