For scientists deeply involved in organic synthesis, peptide chemistry, and medicinal research, understanding the precise chemical properties of key intermediates is paramount. Boc-β-iodo-Ala-OMe, a compound recognized by its CAS number 93267-04-0, is a prime example of such a critical building block. NINGBO INNO PHARMCHEM CO.,LTD. is pleased to share insights into this versatile molecule and its significance in various research applications.

Boc-β-iodo-Ala-OMe is an amino acid derivative characterized by two key structural features: the tert-butyloxycarbonyl (Boc) protecting group and a beta-iodine atom attached to the alanine backbone. The Boc group is a standard protecting group in peptide synthesis, offering stability under various reaction conditions and being easily removable under acidic treatment. This controlled reactivity is vital for building precise peptide sequences.

The presence of the iodine atom at the beta-position is what truly sets Boc-β-iodo-Ala-OMe apart. Iodine is a good leaving group and can participate in a range of nucleophilic substitution and coupling reactions, such as Suzuki, Sonogashira, or Heck couplings, depending on the attached functionalities. This makes the molecule an excellent scaffold for introducing diverse side chains or creating novel amino acid analogs. Researchers often buy Boc-β-iodo-Ala-OMe specifically for these advanced derivatization capabilities.

In research applications, Boc-β-iodo-Ala-OMe is frequently employed in:

  • Peptide Modification: Synthesizing peptides with unnatural amino acids to improve stability, alter conformation, or introduce reporter groups.
  • Medicinal Chemistry: Building libraries of compounds for drug screening, where the iodine can be further functionalized to explore structure-activity relationships (SAR).
  • Bioconjugation: Creating links between peptides and other molecules like proteins, polymers, or surfaces, facilitating drug delivery or diagnostic applications.
  • Radiolabeling: Potentially serving as a precursor for introducing radioactive iodine isotopes for imaging studies.

NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer and supplier of fine chemicals from China, ensures that our Boc-β-iodo-Ala-OMe is produced to the highest standards of purity and consistency. We understand the meticulous nature of chemical research and are committed to providing scientists with reliable access to the materials they need. We encourage all researchers looking for a dependable source of Boc-β-iodo-Ala-OMe to request a quote or inquire about our product specifications.

Partnering with NINGBO INNO PHARMCHEM CO.,LTD. means gaining a supplier that is attuned to the nuances of chemical synthesis and dedicated to supporting your scientific breakthroughs.