In the intricate world of pharmaceutical synthesis, specific chemical intermediates act as foundational building blocks for life-saving medications. Methyl 3-amino-4-methylthiophene-2-carboxylate, identified by CAS number 85006-31-1, stands out as a crucial component, most notably in the synthesis of articaine. Articaine is a widely utilized local anesthetic, appreciated for its effectiveness and rapid onset of action, particularly in dental procedures. Understanding the chemical properties and synthesis pathways involving this thiophene derivative is therefore vital for many pharmaceutical R&D scientists and formulation chemists.

The chemical structure of Methyl 3-amino-4-methylthiophene-2-carboxylate features a thiophene ring substituted with an amino group and a carboxylate ester. This unique arrangement makes it highly reactive and suitable for various synthetic transformations. Its common appearance as a white to light yellow crystal powder, along with a melting point of 85-88°C, provides initial physical identifiers for quality control. Purity levels, typically above 97%, are critical for ensuring the successful and efficient synthesis of downstream pharmaceutical products.

Researchers often seek out this intermediate for its versatility. Beyond its primary application in articaine synthesis, it has been employed in the preparation of other heterocyclic compounds, such as certain thieno[3,2-d]pyrimidin-4(3H)-one derivatives, which are of interest for their potential biological activities. For scientists looking to buy this compound for experimental purposes or scaled production, identifying reputable suppliers who can guarantee consistent quality and provide detailed technical documentation is essential. Many leading chemical companies, including those based in China, offer this product, making it accessible for global research efforts.

The demand for reliable pharmaceutical intermediates like Methyl 3-amino-4-methylthiophene-2-carboxylate underscores the importance of a robust chemical supply chain. For those involved in drug discovery and manufacturing, partnering with a trusted chemical manufacturer that emphasizes stringent quality control and timely delivery is paramount. Exploring options from established chemical providers can offer competitive pricing and ensure that your synthesis projects proceed without interruption. If your work requires this specific thiophene derivative, seeking out well-regarded suppliers for your next purchase will pave the way for successful formulation and development.