In the realm of specialized chemistry, certain molecules serve as linchpins for groundbreaking innovations. 2-Bromo-5-methoxyaniline, identified by its CAS number 59557-92-5, is one such compound. Its unique structural features and reactivity make it an indispensable intermediate in advanced synthesis, particularly for the pharmaceutical and organic electronics (OLED) sectors. For scientists and procurement specialists, understanding its role and how to source it reliably is key.

Chemical Characteristics and Synthesis Basics

2-Bromo-5-methoxyaniline, with the molecular formula C7H8BrNO and molecular weight of 202.05, is an aromatic amine. It typically appears as a brown solid or liquid, with a melting point reported in the range of 189-190°C. Its synthesis often involves reduction steps, such as the reduction of nitro compounds, followed by other chemical modifications to introduce the desired functionalities. Manufacturers focus on optimizing these synthesis routes to achieve high purity levels (commonly 97% or 98%), which is critical for its use in demanding applications. When you plan to buy this chemical, confirming its purity from a trusted manufacturer is a fundamental step.

Impact on Pharmaceutical Innovation

The pharmaceutical industry extensively utilizes 2-Bromo-5-methoxyaniline as a vital intermediate. Its structural framework is instrumental in the synthesis of numerous Active Pharmaceutical Ingredients (APIs). For instance, it's a key precursor in the development of:

  • Epidermal Growth Factor Receptor (EGFR) Inhibitors: These are crucial in targeted cancer therapies.
  • Urolithin Derivatives: Compounds showing potential benefits in metabolic health and anti-aging.
  • Melatonergic Ligands: Investigated for their role in sleep disorders and other neurological conditions.

Researchers in drug discovery constantly seek reliable sources for such intermediates. Understanding the competitive price and availability from reputable suppliers is essential for budgeting and project timelines.

Advancing OLED Technology

Beyond pharmaceuticals, 2-Bromo-5-methoxyaniline plays a significant role in the rapidly evolving field of organic electronics. It is used as a building block in the synthesis of specialized materials for OLEDs. These materials are critical for the performance, efficiency, and color output of modern displays and lighting systems. As demand for brighter, more energy-efficient displays grows, the need for high-quality OLED intermediates like 2-Bromo-5-methoxyaniline also increases. Companies in this sector must ensure they are sourcing from manufacturers who can provide consistent product quality and technical specifications.

For businesses looking to leverage this versatile intermediate, partnering with experienced chemical manufacturers, particularly those in China, offers access to both quality products and cost-effective solutions. Diligent inquiry into purity, production capacity, and supplier reputation will ensure successful procurement.