The Role of 3-Bromo-1,1,1-Trifluoro-2-Propanol in Modern Organic Synthesis
Organic synthesis is the cornerstone of innovation in chemistry, driving advancements in pharmaceuticals, agrochemicals, and materials science. At the heart of complex molecular construction lie versatile building blocks, and 3-Bromo-1,1,1-Trifluoro-2-Propanol (CAS: 88378-50-1) stands out as a particularly valuable one. This fluorinated organic compound, characterized by its trifluoromethyl group and reactive bromine and hydroxyl functionalities, offers synthetic chemists a powerful tool for introducing specific structural motifs. As a prominent manufacturer and supplier from China, we are pleased to highlight the significance of this intermediate in modern organic synthesis and encourage professionals to inquire about purchasing options.
The unique combination of a trifluoromethyl (CF3) group and a bromine atom on a propanol backbone gives 3-Bromo-1,1,1-Trifluoro-2-Propanol (C3H4BrF3O) distinct chemical properties. The CF3 group is known to enhance lipophilicity, metabolic stability, and bioavailability in drug molecules, while the bromine atom serves as an excellent leaving group for nucleophilic substitution and as a handle for palladium-catalyzed cross-coupling reactions. The secondary alcohol group provides another site for functionalization, such as esterification or oxidation. These attributes make it an indispensable intermediate for chemists working on complex target molecules.
For researchers and chemists looking to buy 3-Bromo-1,1,1-Trifluoro-2-Propanol, partnering with a reliable manufacturer and supplier is crucial for consistent quality and availability. Our commitment as a China-based manufacturer ensures that we can supply this high-purity intermediate (98%min) to meet the demanding requirements of advanced synthesis projects. Whether you are synthesizing novel pharmaceuticals, developing next-generation agrochemicals, or exploring new materials, having a trusted source for your key building blocks is essential. We offer competitive pricing for CAS 88378-50-1, making it accessible for both research and development purposes and larger-scale production.
The versatility of 3-Bromo-1,1,1-Trifluoro-2-Propanol extends to its application in creating chiral molecules, as indicated by its (2R) stereochemistry in some contexts, though often supplied as a racemate. Its reactivity profile allows for its integration into a wide range of synthetic strategies, enabling the efficient construction of complex organic frameworks. When considering your next synthesis project, remember the strategic advantage of incorporating trifluoromethyl groups and the utility of bromine as a functional handle. We invite you to contact us for a price inquiry and to learn more about how our dependable supply of this key intermediate can accelerate your research and development efforts.
In summary, 3-Bromo-1,1,1-Trifluoro-2-Propanol is a powerful and versatile building block that plays a significant role in contemporary organic synthesis. By choosing to purchase from a reputable China manufacturer and supplier, you ensure access to a high-purity product essential for innovation. We encourage all professionals in the field to reach out to us for their needs regarding CAS 88378-50-1.
Perspectives & Insights
Agile Reader One
“The versatility of 3-Bromo-1,1,1-Trifluoro-2-Propanol extends to its application in creating chiral molecules, as indicated by its (2R) stereochemistry in some contexts, though often supplied as a racemate.”
Logic Vision Labs
“Its reactivity profile allows for its integration into a wide range of synthetic strategies, enabling the efficient construction of complex organic frameworks.”
Molecule Origin 88
“When considering your next synthesis project, remember the strategic advantage of incorporating trifluoromethyl groups and the utility of bromine as a functional handle.”