Understanding the Chemistry of 3-Bromo-1,1,1-Trifluoro-2-Propanol
For chemists and researchers in the pharmaceutical and agrochemical sectors, a deep understanding of the chemical properties and reactivity of key intermediates is crucial for successful synthesis. 3-Bromo-1,1,1-Trifluoro-2-Propanol (CAS: 88378-50-1) is a prime example of such a compound, offering a unique combination of functional groups that enable diverse chemical transformations. As a leading manufacturer and supplier of this vital intermediate from China, we aim to provide insights into its chemistry to assist researchers and procurement specialists in making informed decisions about purchasing.
The molecular structure of 3-Bromo-1,1,1-Trifluoro-2-Propanol (C3H4BrF3O) is central to its reactivity. It features a secondary alcohol group (-OH), a bromine atom (-Br), and a highly electron-withdrawing trifluoromethyl group (-CF3) attached to a three-carbon chain. The trifluoromethyl group significantly influences the electron density of the molecule, affecting the acidity of the hydroxyl proton and the reactivity of the carbon atoms. The bromine atom, being a good leaving group, facilitates nucleophilic substitution reactions, while the alcohol group can participate in esterification, etherification, or oxidation reactions. These characteristics make it an exceptionally versatile building block in organic synthesis.
When considering how to buy 3-Bromo-1,1,1-Trifluoro-2-Propanol, it's important to recognize its potential applications. For instance, the bromine atom can be readily displaced by various nucleophiles, allowing for the introduction of different functional groups. Alternatively, it can be employed in metal-catalyzed cross-coupling reactions to form new carbon-carbon bonds, a cornerstone of modern synthetic chemistry. The presence of the CF3 group often confers enhanced stability and lipophilicity to the resulting molecules, properties highly sought after in drug discovery and agrochemical development. For researchers looking to buy this compound, a reliable supplier like ourselves, offering high purity (98%min) and technical support, is invaluable.
The compound's boiling point of approximately 124.5℃ at 760mmHg and flash point of 43.3℃ also provide essential handling and processing information for chemists. As a reputable China-based manufacturer and supplier, we ensure that our product adheres to strict specifications. We encourage professionals to submit a price inquiry for our CAS 88378-50-1 to explore its potential in their synthesis strategies. Understanding the chemical behavior of this intermediate is key to unlocking its full synthetic potential.
In summary, the chemistry of 3-Bromo-1,1,1-Trifluoro-2-Propanol is characterized by the synergistic effects of its trifluoromethyl, bromine, and hydroxyl groups. This makes it an indispensable intermediate for complex organic synthesis. As a dedicated China manufacturer and supplier, we are committed to providing high-quality CAS 88378-50-1 to support your chemical research and development. We invite you to contact us to discuss your specific needs and procurement requirements.
Perspectives & Insights
Nano Explorer 01
“The bromine atom, being a good leaving group, facilitates nucleophilic substitution reactions, while the alcohol group can participate in esterification, etherification, or oxidation reactions.”
Data Catalyst One
“These characteristics make it an exceptionally versatile building block in organic synthesis.”
Chem Thinker Labs
“When considering how to buy 3-Bromo-1,1,1-Trifluoro-2-Propanol, it's important to recognize its potential applications.”