Pharmaceutical manufacturing relies on a precise and consistent supply of high-quality chemical intermediates. Among these, 8-[(2-hydroxybenzoyl)amino]octanoic acid stands out as a critical component for developing advanced drug delivery systems. Known also as salcaprozic acid, this compound is essential for enhancing the oral bioavailability of various therapeutic agents, particularly macromolecules like peptides and proteins.

As a leading manufacturer and supplier, we are dedicated to providing the pharmaceutical industry with the essential building blocks for innovation. Our 8-[(2-hydroxybenzoyl)amino]octanoic acid, CAS 183990-46-7, is synthesized with exceptional purity (>99%) to meet the stringent quality requirements of pharmaceutical applications.

Understanding the Functionality of 8-[(2-hydroxybenzoyl)amino]octanoic Acid

The primary utility of 8-[(2-hydroxybenzoyl)amino]octanoic acid in pharmaceutical manufacturing stems from its function as an intestinal permeation enhancer. It actively facilitates the absorption of drugs that would otherwise have poor oral uptake due to enzymatic degradation or low permeability across the intestinal lining. Its key contributions include:

  • Protecting Drugs from Degradation: In the stomach, it helps maintain a favorable local pH environment, safeguarding sensitive peptide-based drugs from enzymatic breakdown.
  • Improving Membrane Passage: It transiently modifies the intestinal cell membranes, enhancing the passive transport of drug molecules through a transcellular pathway.
  • Facilitating Oral Formulations: This makes it possible to develop effective oral dosage forms for many drugs that traditionally required injection, thereby improving patient convenience and adherence.

This compound has been instrumental in advancements such as the development of oral semaglutide, a breakthrough treatment for type 2 diabetes, highlighting its significant impact on patient care.

Why Choose Our 8-[(2-hydroxybenzoyl)amino]octanoic Acid?

For pharmaceutical manufacturers, sourcing reliable and high-purity intermediates is non-negotiable. Our company offers:

  • Exceptional Purity: We guarantee a consistently high level of purity, ensuring the integrity and efficacy of your final drug product.
  • Stable Supply: As a dedicated manufacturer, we provide a reliable and consistent supply chain to meet your production demands.
  • Competitive Pricing: We offer competitive pricing for bulk orders, supporting cost-effective pharmaceutical manufacturing.

By incorporating our 8-[(2-hydroxybenzoyl)amino]octanoic acid into your manufacturing processes, you can enhance the performance of your oral drug formulations and contribute to better patient outcomes. We are committed to being a trusted partner in your pharmaceutical development journey.

We invite pharmaceutical companies seeking a dependable supplier of this critical intermediate to contact us. Learn more about our product specifications and how we can support your manufacturing needs with high-quality 8-[(2-hydroxybenzoyl)amino]octanoic acid. Secure your supply from a trusted manufacturer today.