The Role of Boc-His(Bom)-OH in Pharmaceutical Research & Development
The pharmaceutical industry constantly seeks innovative solutions for disease treatment, with peptide-based therapeutics gaining significant traction due to their specificity and efficacy. At the heart of synthesizing these complex molecules lies a range of specialized chemical intermediates, among which Boc-His(Bom)-OH (CAS: 79950-65-5) holds a position of importance. This article aims to shed light on the critical role of this protected histidine derivative in pharmaceutical research and development (R&D), emphasizing the value of sourcing it from a reliable manufacturer.
Boc-His(Bom)-OH, scientifically known as N-tert-butyloxycarbonyl-N'-benzyloxymethyl-L-histidine, is a protected form of the amino acid histidine. Its protected nature makes it an ideal candidate for use in peptide synthesis, a core technology in modern drug discovery. The Boc protection on the alpha-amino group and the Bom protection on the imidazole side chain of histidine allow for controlled, sequential addition of amino acids during peptide chain assembly. This prevents premature reactions and ensures the correct sequence is built, which is vital for the biological activity of the final peptide drug candidate.
For pharmaceutical R&D teams, the consistent availability of high-purity Boc-His(Bom)-OH is non-negotiable. Impurities in such crucial intermediates can lead to failed syntheses, inaccurate results, and significant delays in drug development timelines. Therefore, partnering with a trusted chemical supplier and manufacturer, particularly one based in China with strong production capabilities, is essential. We pride ourselves on being such a supplier, offering Boc-His(Bom)-OH that meets rigorous quality standards, ensuring it performs optimally in demanding pharmaceutical applications.
The applications of Boc-His(Bom)-OH in pharmaceutical R&D are diverse. It is used in the synthesis of peptide hormones, signaling peptides, and peptide mimetics that target various diseases, from metabolic disorders to oncology. Its incorporation allows researchers to fine-tune the properties of peptide drugs, such as solubility, stability, and receptor binding affinity. The ability to purchase Boc-His(Bom)-OH in required quantities and with guaranteed purity empowers research scientists to push the boundaries of peptide-based drug design.
When seeking to buy Boc-His(Bom)-OH, consider the entire value proposition offered by a supplier: product quality, consistency, pricing, and customer support. As a manufacturer, we are dedicated to providing comprehensive technical data and responsive service to assist procurement managers and R&D professionals. Our aim is to be more than just a supplier; we aim to be a reliable partner in your pharmaceutical R&D journey, ensuring you have access to the high-quality chemical intermediates you need, precisely when you need them.
Perspectives & Insights
Logic Thinker AI
“Therefore, partnering with a trusted chemical supplier and manufacturer, particularly one based in China with strong production capabilities, is essential.”
Molecule Spark 2025
“We pride ourselves on being such a supplier, offering Boc-His(Bom)-OH that meets rigorous quality standards, ensuring it performs optimally in demanding pharmaceutical applications.”
Alpha Pioneer 01
“It is used in the synthesis of peptide hormones, signaling peptides, and peptide mimetics that target various diseases, from metabolic disorders to oncology.”