The intricate regulation of glucose homeostasis is vital for overall health, and disruptions can lead to metabolic disorders like type 2 diabetes. A key player in this complex system is the liver, responsible for producing glucose to maintain blood sugar levels. Research into novel therapeutic targets for these conditions often focuses on enzymes that control energy substrate utilization within hepatocytes. Among these, carnitine palmitoyltransferase 1A (L-CPT1) stands out due to its critical role in fatty acid oxidation.

Carnitine palmitoyltransferase 1A (L-CPT1) is an enzyme located on the outer mitochondrial membrane. Its primary function is to facilitate the transport of long-chain fatty acids into the mitochondria, where they undergo beta-oxidation to generate ATP. This process is crucial for providing energy to the cell. However, under certain conditions, such as fasting or prolonged exercise, the liver increases glucose production through gluconeogenesis to supply the body with energy. The availability of fatty acids as an alternative fuel source influences the rate of gluconeogenesis; when fatty acids are readily oxidized, the liver may rely less on glucose production.

This is where compounds like Teglicar (CAS 250694-07-6) become scientifically significant. Teglicar is a selective and reversible inhibitor of L-CPT1. By inhibiting this enzyme, Teglicar effectively reduces the entry of fatty acids into the mitochondria for oxidation. This disruption of fatty acid metabolism has a direct impact on hepatic glucose production. When fatty acid oxidation is limited, the liver's dependence on gluconeogenesis can increase, potentially leading to improved glucose homeostasis. This mechanism highlights Teglicar's potential utility in research aimed at understanding and managing conditions characterized by impaired glucose metabolism.

For researchers focused on diabetes and metabolic syndrome, acquiring high-quality Teglicar is essential. As a reputable manufacturer and supplier in China, we provide Teglicar (CAS 250694-07-6) with guaranteed purity for laboratory applications. Understanding how to buy Teglicar for your studies allows you to explore its effects on gluconeogenesis and insulin sensitivity. Our commitment is to be your trusted source, offering reliable supply and competitive pricing for this important metabolic research chemical. Purchasing Teglicar from us ensures you receive a product that meets stringent research standards, supporting your critical work in understanding and combating metabolic disorders.