Trans-1,2-cyclohexanedicarboxylic acid (CAS: 2305-32-0) is more than just a chemical compound; it's a vital component in numerous advanced synthesis pathways. As a white crystalline powder, this molecule plays a crucial role as an intermediate in the pharmaceutical sector and the broader fine chemical industry. Understanding its synthesis and industrial relevance is key for R&D scientists and procurement specialists.

Synthesis Pathways and Chemical Properties

The preparation of trans-1,2-cyclohexanedicarboxylic acid typically involves the hydrolysis of its anhydride or related precursors. The molecule's structure, featuring two carboxylic acid groups on a cyclohexane ring in a trans configuration, dictates its reactivity. With a purity often exceeding 98.0%, it offers the consistency required for demanding chemical reactions. Its physical properties, such as a melting point around 228-230°C, also contribute to its ease of handling and storage.

Industrial Applications and Market Demand

The industrial demand for trans-1,2-cyclohexanedicarboxylic acid is largely driven by its applications:

  • Pharmaceutical Intermediates: It is fundamental in synthesizing specific drug candidates, including those targeting osteoarthritis (via cathepsin K inhibitors) and chronic pain (via sodium channel blockers). For pharmaceutical manufacturers, securing a reliable supply of this intermediate is a strategic imperative when they look to buy necessary raw materials.
  • Organic Synthesis: Beyond pharmaceuticals, it serves as a versatile reagent in general organic synthesis, enabling the creation of complex molecules for various industrial applications.
  • Specialty Chemicals: Its unique structure can be leveraged in the development of novel materials and specialty chemicals, highlighting its broad utility.

For businesses seeking to procure this essential chemical, identifying reliable manufacturers and suppliers is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated provider of high-quality trans-1,2-cyclohexanedicarboxylic acid, committed to supporting your synthesis and production needs. We offer competitive pricing and a stable supply chain, ensuring you can buy with confidence. Contact us today to request a quotation and discuss your specific requirements for this important chemical building block.