For professionals in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is paramount to successful product development. One such crucial compound is 1-Methyl-3-phenyl-1H-pyrazol-5-amine, identified by its CAS number 10199-50-5. Understanding its properties and how to procure it reliably can significantly impact research and manufacturing timelines.

What is 1-Methyl-3-phenyl-1H-pyrazol-5-amine?

This compound is a heterocyclic organic molecule belonging to the pyrazole family. Its chemical structure, C10H11N3, with a molecular weight of 173.21 g/mol, makes it a valuable building block in organic synthesis. It typically presents as a white to yellow solid, with a reported melting point range of 125-128°C. Its high purity, often exceeding 99%, is critical for its applications, especially in pharmaceutical research and development.

Why is it Important in Pharmaceutical Synthesis?

The pyrazole scaffold is a 'privileged structure' in medicinal chemistry, meaning it frequently appears in biologically active compounds. 1-Methyl-3-phenyl-1H-pyrazol-5-amine serves as a versatile intermediate for synthesizing a wide array of complex molecules. Researchers utilize it to create novel drug candidates, agrochemicals, and specialty materials. Its reactive amine group and the pyrazole ring system allow for diverse functionalization and cyclization reactions, leading to compounds with potential therapeutic properties such as antimicrobial, anti-inflammatory, or anticancer activities.

Key Considerations When Buying

When looking to buy 1-Methyl-3-phenyl-1H-pyrazol-5-amine, several factors should guide your selection process:

  • Purity Levels: Always verify the purity offered by the manufacturer. For pharmaceutical applications, 99% purity is often the minimum requirement.
  • Supplier Reliability: Choose a manufacturer with a proven track record in producing and supplying fine chemicals. A reliable supplier ensures consistent quality and timely delivery.
  • Technical Specifications: Ensure the provided specifications (CAS number, molecular formula, melting point, appearance) match your project's needs.
  • Pricing and Availability: Compare pricing from different suppliers and inquire about stock availability or lead times for custom synthesis. Requesting a quote is a standard first step.

Finding a Manufacturer in China

China is a significant hub for chemical manufacturing, offering competitive pricing and a vast capacity for production. When sourcing 1-Methyl-3-phenyl-1H-pyrazol-5-amine from China, it's essential to partner with reputable manufacturers. Look for suppliers who provide detailed Certificates of Analysis (CoA), excellent customer service, and are transparent about their production capabilities. Many manufacturers offer free samples, allowing you to assess product quality before committing to a bulk purchase. Inquire about their manufacturing processes and quality control measures to ensure you are obtaining a product that meets international standards.

In conclusion, for your pharmaceutical synthesis and advanced organic chemistry needs, securing a dependable source of high-purity 1-Methyl-3-phenyl-1H-pyrazol-5-amine is crucial. By understanding its chemical properties and focusing on reliable manufacturers, you can effectively drive your research and production forward. If you are looking to purchase this intermediate, remember to request a quote and explore sample options from trusted chemical suppliers.