For procurement managers in the pharmaceutical and fine chemical industries, sourcing critical intermediates like 2,3-Dihydrobenzofuran-5-carbaldehyde (CAS 55745-70-5) is a meticulous process. Ensuring high purity, consistent supply, and competitive pricing are paramount. This guide aims to equip you with the knowledge to effectively buy this vital building block.

Understanding the product is the first step. 2,3-Dihydrobenzofuran-5-carbaldehyde is primarily recognized for its role as a pharmaceutical intermediate, most notably in the synthesis of Ramelteon, a widely used sleep aid. Its chemical structure, C9H8O2, and molecular weight of approximately 148.16 g/mol, along with an aldehyde functional group, dictate its reactivity and applications in complex organic synthesis. When you search for this compound, look for specifications like 'CAS 55745-70-5' and purity levels typically above 96.0% (GC), with many manufacturers offering ≥98.0%.

When selecting a supplier, consider their manufacturing capabilities and quality control measures. Reputable manufacturers often provide detailed Certificates of Analysis (CoA), Material Safety Data Sheets (MSDS), and support for regulatory documentation like DMFs. For procurement managers in China, identifying manufacturers with a strong track record in producing pharmaceutical intermediates is key. This includes assessing their production capacity, their adherence to international quality standards, and their ability to handle custom synthesis requirements if needed.

Pricing for 2,3-Dihydrobenzofuran-5-carbaldehyde can vary based on purity, quantity, and supplier. Obtaining multiple quotes from established manufacturers and suppliers is a standard practice. Negotiating bulk purchase agreements can lead to significant cost savings, making it more feasible to incorporate this intermediate into large-scale production lines. Remember to inquire about Incoterms (like FOB, CFR, CIF) to understand the total landed cost.

Furthermore, reliable packaging and storage are crucial for maintaining the compound's integrity. Suppliers typically offer packaging in drums (e.g., 200 kg) or smaller containers as per buyer requests, with recommendations for storage in cool, well-ventilated areas. Understanding these logistical aspects ensures that the product arrives in optimal condition, ready for use in your manufacturing processes.

In conclusion, when looking to buy 2,3-Dihydrobenzofuran-5-carbaldehyde, prioritize suppliers who offer a combination of high purity, manufacturing expertise, reliable supply chains, and competitive pricing. By focusing on these factors, procurement professionals can secure the essential materials needed for successful pharmaceutical development and fine chemical production.