In the fast-paced world of chemical procurement, sourcing high-quality intermediates is paramount for successful research and manufacturing. For professionals dealing with pharmaceutical synthesis and advanced materials, 2-Bromo-3-methylthiophene (CAS: 14282-76-9) stands out as a critical building block. This article serves as a guide for procurement managers looking to understand its value and identify reliable suppliers.

Understanding the Value of 2-Bromo-3-methylthiophene

2-Bromo-3-methylthiophene is a heterocyclic organic compound that plays a significant role in various industries. Its chemical structure, featuring a thiophene ring with a bromine atom and a methyl group, imparts unique reactivity. This makes it an indispensable intermediate in several key applications:

  • Pharmaceutical Intermediates: It is widely recognized for its use in the synthesis of Active Pharmaceutical Ingredients (APIs), notably as a precursor for Tiagabine hydrochloride. For pharmaceutical companies, the purity and consistency of this intermediate directly impact the efficacy and safety of the final drug product. Procurement managers must prioritize suppliers who can guarantee high assay values, such as ≥99.0%, to ensure batch-to-batch reproducibility.
  • Material Science and Organic Electronics: The compound is also a valuable component in the development of advanced materials. Its inclusion in the synthesis of conductive polymers and organic semiconductors contributes to the performance of electronic devices like OLEDs. Researchers in material science often seek this compound to explore novel electronic properties.
  • Organic Synthesis: Beyond these primary areas, 2-Bromo-3-methylthiophene serves as a versatile building block in general organic synthesis, enabling the creation of more complex molecular structures for various industrial and research purposes.

Key Considerations for Procurement: Quality, Purity, and Supply Stability

When sourcing 2-Bromo-3-methylthiophene, procurement managers should focus on several critical factors:

  • Purity Levels: As mentioned, a purity of ≥99.0% is typically desired to avoid impurities that could interfere with reactions or degrade product quality. Always request a Certificate of Analysis (CoA) from potential suppliers.
  • Physical Properties: The compound is commonly described as a light yellow transparent liquid, with a boiling point around 177°C. Understanding these properties helps in handling, storage, and process integration.
  • Supplier Reliability: Identifying a reputable manufacturer or supplier in China is crucial for ensuring a stable supply chain. Factors to consider include production capacity, adherence to quality standards (like ISO certifications), and responsive customer service. For bulk purchases, negotiating favorable pricing and delivery schedules is essential.
  • Regulatory Compliance: While not explicitly detailed for this specific compound in all sources, understanding any relevant Hazmat classifications or handling requirements is part of due diligence.

Finding a Trusted Supplier

For businesses looking to buy 2-Bromo-3-methylthiophene, several Chinese manufacturers and suppliers offer this chemical. When evaluating them, consider their experience, product specifications, packaging options (e.g., 25 kg/drum), and their ability to provide timely technical support and documentation. Engaging with a well-established manufacturer ensures not only competitive pricing but also a commitment to long-term supply and quality assurance. If you are exploring options for the synthesis of Tiagabine hydrochloride intermediate or other specialized applications, partnering with a trusted provider of 2-Bromo-3-methylthiophene is a strategic decision.

By prioritizing these aspects, procurement managers can effectively source high-quality 2-Bromo-3-methylthiophene, ensuring the success of their projects and maintaining a competitive edge in their respective industries. To learn more about availability or to get a quote for your specific needs, reach out to leading suppliers in the market.