For procurement managers in the pharmaceutical industry, sourcing reliable intermediates is paramount. 2-Chloro-3-pyridinamine (CAS 6298-19-7) stands out as a crucial building block, underpinning the synthesis of numerous Active Pharmaceutical Ingredients (APIs). Understanding its properties, applications, and the supplier landscape, especially within China, is key to ensuring a stable and cost-effective supply chain.

Understanding 2-Chloro-3-pyridinamine

Also known by its synonyms such as 2-chloro-3-aminopyridine or 3-amino-2-chloropyridine, this compound (C5H5ClN2) presents as an off-white to yellow to pink crystalline powder. Its significance lies in its chemical structure, which makes it a highly versatile intermediate in organic synthesis. Specifically, it is frequently employed in Suzuki-Miyaura cross-coupling reactions, a powerful method for creating carbon-carbon bonds essential for constructing complex molecular architectures found in pharmaceuticals.

Why Source from China? The Manufacturer Advantage

China has emerged as a global powerhouse for fine chemical manufacturing, offering significant advantages in terms of production scale, cost-efficiency, and technological advancement. When looking to buy 2-Chloro-3-pyridinamine, partnering with a reputable Chinese manufacturer can provide access to high-purity material (often ≥99%) at competitive prices. These manufacturers often have robust quality control systems and the capacity to meet large-volume demands, ensuring continuity for your production lines.

Key Considerations for Pharmaceutical Buyers

  • Purity and Specifications: Confirm that the supplier can consistently deliver 2-Chloro-3-pyridinamine meeting your required purity levels and specifications, typically ≥99%. Understanding the CAS number (6298-19-7) is crucial for accurate product identification.
  • Supplier Reliability: Vet potential manufacturers for their production capacity, quality certifications (like ISO), and track record in international trade. A stable supply chain is non-negotiable in pharmaceutical manufacturing.
  • Pricing and Negotiation: Obtain quotes from multiple suppliers to benchmark prices. Consider factors like minimum order quantities (MOQ) and payment terms. Inquiring about bulk purchase discounts for intermediates like 2-chloro-3-aminopyridine can lead to significant cost savings.
  • Logistics and Lead Times: Understand the shipping options (air, sea, courier) and estimated lead times from China to your location. Efficient logistics are vital for maintaining production schedules.

The Role in Drug Synthesis

2-Chloro-3-pyridinamine serves as a fundamental building block for a variety of drug candidates. Its pyridine ring structure, functionalized with both an amine and a chlorine atom, allows for diverse chemical modifications. Pharmaceutical researchers and formulators often seek this compound for its predictable reactivity and its contribution to the biological activity of the final drug product.

Conclusion

For pharmaceutical companies, securing a dependable source of 2-Chloro-3-pyridinamine is a strategic imperative. By focusing on reputable Chinese manufacturers, understanding the product's specifications, and optimizing the procurement process, buyers can ensure they obtain this vital intermediate efficiently and economically. We are committed to being a trusted supplier, offering high-quality 2-chloro-3-pyridinamine to meet the demanding needs of the pharmaceutical industry. Contact us today to learn more about our product offerings and to request a quote.