For procurement managers and research scientists in the pharmaceutical and agrochemical sectors, securing a consistent and high-quality supply of essential intermediates is paramount. 2-Chloro-5-fluoro-3-nitropyridine (CAS: 136888-21-6) is one such compound, a versatile organic building block that plays a critical role in the synthesis of advanced molecules. This article aims to guide you through the process of sourcing this vital chemical, emphasizing key considerations when looking for a reliable manufacturer and supplier, particularly within China.

Understanding the Importance of 2-Chloro-5-fluoro-3-nitropyridine

This specialized pyridine derivative, characterized by its unique combination of chlorine, fluorine, and nitro functional groups, offers exceptional reactivity. This makes it an ideal precursor for a wide range of complex organic syntheses. Its applications span from the development of novel Active Pharmaceutical Ingredients (APIs) to the formulation of next-generation agrochemicals. The precise molecular structure and purity of this intermediate directly influence the efficacy and safety of the final products, underscoring the need for careful supplier selection.

Key Factors When Buying 2-Chloro-5-fluoro-3-nitropyridine

When you decide to buy 2-Chloro-5-fluoro-3-nitropyridine, several factors should guide your decision-making process:

  • Purity: Aim for products with a purity of 98% or higher, as confirmed by analytical methods like HPLC or GC. High purity ensures predictable reaction outcomes and minimizes the risk of unwanted byproducts.
  • CAS Number Verification: Always confirm the CAS number (136888-21-6) to ensure you are procuring the correct chemical entity.
  • Supplier Reputation and Reliability: Partner with established manufacturers or distributors who have a proven track record in producing and supplying fine chemicals. Look for suppliers who can provide comprehensive documentation, including Certificates of Analysis (CoA) and Safety Data Sheets (SDS).
  • Price and Volume: While competitive pricing is essential, it should not come at the expense of quality. Discuss bulk purchase options and pricing structures with potential suppliers. Manufacturers in China often provide cost-effective solutions for high-volume orders.
  • Technical Support and Customization: A good supplier will offer technical support and be willing to discuss custom synthesis or packaging needs if required.

Navigating the China Supply Chain

China has established itself as a global leader in the production of chemical intermediates. Many Chinese manufacturers are adept at synthesizing compounds like 2-Chloro-5-fluoro-3-nitropyridine with high efficiency and adherence to international quality standards. When seeking a 2-Chloro-5-fluoro-3-nitropyridine manufacturer in China, focus on those with robust quality control systems, advanced production capabilities, and a commitment to customer service. Companies that specialize in pharmaceutical intermediates and offer services like custom synthesis are particularly valuable partners.

Requesting Quotes and Samples

The best way to assess a supplier is to request detailed quotations and, if possible, samples. This allows you to verify the product's quality and consistency firsthand. When you contact a supplier, clearly state your requirements, including the desired quantity, purity specifications, and intended application. This proactive approach will help you secure a reliable source for 2-Chloro-5-fluoro-3-nitropyridine and build a strong, long-term partnership for your procurement needs.

For those looking to buy 2-Chloro-5-fluoro-3-nitropyridine and ensure a stable supply chain, engaging with reputable Chinese manufacturers is a strategic advantage. By focusing on quality, reliability, and clear communication, you can secure this critical organic intermediate for your ongoing research and production.