For procurement managers and R&D scientists in the pharmaceutical sector, sourcing high-quality chemical intermediates is paramount. 3-Pyridineacrylic Acid, identified by its CAS number 19337-97-4, stands out as a critical building block in the synthesis of various active pharmaceutical ingredients (APIs). Understanding its properties and how to procure it effectively can significantly streamline your development and manufacturing processes.

Understanding 3-Pyridineacrylic Acid (CAS 19337-97-4)
3-Pyridineacrylic Acid is an organic compound characterized by a pyridine ring attached to an acrylic acid moiety. Its chemical formula is C8H7NO2, with a molecular weight of approximately 149.147 g/mol. Commonly observed as a yellow crystalline powder, it typically boasts a high purity, often exceeding 99% min, making it suitable for sensitive pharmaceutical applications. Its melting point is generally in the range of 232-235°C, indicating its solid state at room temperature.

Key Applications in Pharmaceutical Synthesis
The primary utility of 3-Pyridineacrylic Acid lies in its role as a versatile intermediate. Its unique structure, featuring both a pyridine nitrogen and a carboxylic acid group, allows it to participate in a wide array of chemical reactions. It is frequently employed in:

  • API Synthesis: As a key precursor, it is integral to the development of new drug molecules targeting various therapeutic areas.
  • Heterocyclic Chemistry: Its pyridine core makes it valuable for constructing complex heterocyclic systems found in many pharmaceuticals.
  • Organic Synthesis: It serves as a functionalized building block in multi-step synthesis pathways, enabling the precise introduction of specific chemical functionalities.

Navigating the Procurement Process: What Buyers Need to Know
When looking to purchase 3-Pyridineacrylic Acid, buyers should focus on several key aspects to ensure a successful transaction and a reliable supply. Understanding typical specifications and market dynamics is crucial.

  • Purity Requirements: For pharmaceutical applications, a minimum purity of 99% is often essential to ensure product efficacy and safety. Always verify the purity specifications provided by the manufacturer.
  • Supplier Reliability: Partnering with reputable manufacturers and suppliers is vital. Look for suppliers with a proven track record in delivering quality chemicals, preferably those with a strong presence in China, known for its robust chemical manufacturing sector.
  • Pricing and Quotes: Obtaining multiple quotes is a standard procurement practice. When inquiring about the price of 3-Pyridineacrylic Acid, be prepared to specify the quantity and desired purity. Manufacturers in China often offer competitive pricing due to economies of scale and efficient production processes.
  • Technical Data and Support: A good supplier will readily provide Certificates of Analysis (CoA), Material Safety Data Sheets (MSDS), and technical support to assist with your specific application queries.

Why Choose a Chinese Manufacturer for 3-Pyridineacrylic Acid?
China has emerged as a global hub for chemical manufacturing, offering significant advantages in terms of cost-effectiveness, production capacity, and a wide range of available intermediates. For procurement managers seeking to buy 3-Pyridineacrylic Acid, sourcing from a reliable Chinese manufacturer can offer substantial benefits. These include competitive pricing due to lower manufacturing costs and efficient supply chains, as well as access to a broad spectrum of chemical expertise. Companies that prioritize quality control and adhere to international standards are well-positioned to be valuable partners.

In conclusion, for any pharmaceutical company or research institution requiring 3-Pyridineacrylic Acid (CAS 19337-97-4), diligent sourcing from qualified manufacturers in China is a strategic move. By focusing on purity, supplier reputation, and competitive pricing, you can secure a consistent and high-quality supply of this essential intermediate, thereby supporting your ongoing innovation and production needs.