For procurement managers and R&D scientists in the pharmaceutical sector, sourcing high-quality chemical intermediates is paramount. 4,7-Dichloroquinoline (CAS 86-98-6) stands out as a crucial building block, primarily for the synthesis of essential antimalarial drugs such as chloroquine and hydroxychloroquine. Understanding where and how to procure this vital compound can significantly impact your project's success, cost-effectiveness, and supply chain reliability. This guide aims to provide insights into sourcing 4,7-Dichloroquinoline, focusing on quality, pricing, and the advantages of partnering with established manufacturers.

Understanding 4,7-Dichloroquinoline: Properties and Applications

4,7-Dichloroquinoline is a heterocyclic organic compound with the molecular formula C9H5Cl2N and a molecular weight of 198.05 g/mol. It typically appears as a white to light yellow crystal powder. Its significance lies in its role as a key intermediate in the pharmaceutical industry. The reactivity of the chlorine atom at the 4-position makes it an ideal starting material for nucleophilic aromatic substitution reactions, allowing for the introduction of various amine side chains that are characteristic of many antimalarial drugs. Its CAS number, 86-98-6, is a globally recognized identifier, essential for accurate procurement and regulatory compliance.

Key Considerations When Buying 4,7-Dichloroquinoline

When you intend to buy 4,7-Dichloroquinoline, several factors demand careful consideration to ensure you are obtaining a product that meets your stringent requirements:

  • Purity and Quality: For pharmaceutical applications, the purity of 4,7-Dichloroquinoline is non-negotiable. High purity levels (often 99%+) are critical to ensure the efficacy and safety of the final Active Pharmaceutical Ingredient (API). Look for suppliers who provide detailed Certificates of Analysis (COA) with lot-specific data.
  • Supplier Reliability: Establishing a relationship with a dependable manufacturer or supplier is vital for consistent supply. A reliable supplier will have robust quality control systems, stable production capacity, and a proven track record in the chemical industry.
  • Pricing: While quality is paramount, competitive pricing is also a significant factor, especially for bulk purchases. Understanding market rates and obtaining multiple quotes can help secure cost-effective sourcing. Consider the total cost of ownership, including shipping and potential import duties.
  • Lead Times and Delivery: For R&D projects and ongoing manufacturing, timely delivery is crucial. Inquire about production lead times and shipping options to ensure your supply chain remains uninterrupted.
  • Regulatory Compliance: Ensure that the supplier adheres to relevant international quality standards and provides necessary documentation for customs and regulatory purposes.

The Advantage of Sourcing from China

China has emerged as a global hub for chemical manufacturing, offering a vast array of high-quality intermediates at competitive prices. When sourcing 4,7-Dichloroquinoline, manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., often provide:

  • Large-Scale Production Capabilities: Enabling them to meet demands for bulk orders.
  • Cost Efficiencies: Leading to more favorable pricing for buyers.
  • Extensive Export Experience: Facilitating smooth international transactions and logistics.
  • Commitment to Quality: Many Chinese manufacturers are increasingly focused on international quality standards, including ISO certifications.

How to Get a Quote for 4,7-Dichloroquinoline?

To obtain a quote for 4,7-Dichloroquinoline and discuss your specific requirements, it's best to contact reputable chemical suppliers directly. When you reach out to a manufacturer like NINGBO INNO PHARMCHEM CO.,LTD., be prepared to provide details such as the quantity needed, desired purity grade, and delivery timeline. This information will help them provide an accurate and timely quotation. Engaging with experienced suppliers ensures you get not only the product but also the technical support and logistical expertise needed for successful procurement.

In conclusion, sourcing 4,7-Dichloroquinoline requires a strategic approach, prioritizing quality, supplier reliability, and cost-effectiveness. By understanding these factors and partnering with established manufacturers, your organization can ensure a stable supply of this critical intermediate, facilitating the development and production of life-saving antimalarial drugs. For inquiries and quotes, we encourage you to connect with leading suppliers in the field.