For professionals in the pharmaceutical industry, securing high-quality chemical intermediates is paramount to successful drug development and manufacturing. Among these essential building blocks is 4-Bromophenylacetonitrile (CAS 16532-79-9). This article serves as a comprehensive guide for API manufacturers looking to understand the importance of this compound and how to effectively source it, emphasizing the benefits of partnering with a reputable manufacturer and supplier in China.

Understanding 4-Bromophenylacetonitrile (CAS 16532-79-9)

4-Bromophenylacetonitrile, also known by its IUPAC name 2-(4-bromophenyl)acetonitrile, is a critical organic compound widely used as an intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its molecular structure, featuring a brominated phenyl ring attached to an acetonitrile group, makes it a versatile starting material for a myriad of organic reactions, including nucleophilic substitutions and further functionalization. Typically appearing as a colorless to pale brown crystalline mass, its purity, often specified at ≥99%, is a key factor for its utility in pharmaceutical applications where stringent quality controls are essential.

Why is High Purity Crucial for API Synthesis?

In the realm of pharmaceutical manufacturing, the purity of intermediates directly impacts the efficacy, safety, and stability of the final API. Impurities present in 4-Bromophenylacetonitrile can lead to the formation of unwanted by-products during synthesis, complicating purification processes, reducing overall yield, and potentially introducing toxicological risks. Therefore, sourcing material with a guaranteed high purity, such as the ≥99% grade, is not merely a preference but a necessity for API manufacturers aiming for compliance with regulatory standards like GMP (Good Manufacturing Practice).

The Strategic Advantage of Sourcing from China Manufacturers

China has emerged as a global powerhouse in chemical manufacturing, offering a vast array of intermediates at competitive price points. For companies seeking to buy 4-Bromophenylacetonitrile, a Chinese manufacturer and supplier often presents a compelling combination of quality, volume, and cost-effectiveness. Reputable Chinese manufacturers invest heavily in advanced production technologies and quality control systems to meet international standards. By establishing relationships with these suppliers, businesses can benefit from stable supply chains, bulk purchasing power, and expertise in large-scale production. When looking to purchase this chemical, understanding the supplier's certifications, production capacity, and export capabilities is vital.

Navigating the Procurement Process

When you are ready to acquire 4-Bromophenylacetonitrile, consider the following steps to ensure a smooth procurement process:

  • Identify Reputable Suppliers: Look for manufacturers with established track records and certifications.
  • Request Quotations: Obtain detailed price quotes, including terms for volume discounts and payment methods (L/C, T/T, etc.).
  • Verify Specifications: Confirm that the product meets your required purity levels and physical form. Request a Certificate of Analysis (CoA).
  • Discuss Packaging and Logistics: Clarify packaging options and shipping terms (FOB, CIF, etc.), and inquire about minimum order quantities (MOQ) or minimum order sizes (e.g., 10 Grams for samples).
  • Understand Lead Times: Factor in production and shipping times to align with your project timelines.

As a dedicated manufacturer and supplier, we understand the critical needs of the pharmaceutical industry. We are committed to providing high-purity 4-Bromophenylacetonitrile (CAS 16532-79-9) to support your API synthesis projects. Contact us today to discuss your requirements, request a quote, and secure a reliable supply of this essential intermediate for your operations.