For professionals in the pharmaceutical industry, securing high-quality raw materials is paramount. 5-Amino-2,3-dichloropyridine (CAS: 98121-41-6) stands out as a critical intermediate in the synthesis of various APIs. Understanding its properties, applications, and the nuances of sourcing this compound is key to successful drug development and manufacturing.

Understanding 5-Amino-2,3-dichloropyridine

This heterocyclic organic compound, identified by CAS number 98121-41-6, is characterized by its pyridine ring structure with an amino group and two chlorine substituents. Its molecular formula is C5H4Cl2N2, and it typically appears as a white to light yellow or orange crystalline powder. The melting point range of 107-112°C is a significant indicator of its purity and physical state, crucial for formulators and R&D scientists.

Key Applications in Pharmaceutical Synthesis

The primary utility of 5-Amino-2,3-dichloropyridine lies in its role as a versatile building block in organic synthesis. Pharmaceutical researchers and product formulators utilize it to construct complex molecular architectures, leading to the development of novel drug candidates. Its reactive sites allow for various chemical transformations, making it invaluable for creating diverse pharmaceutical intermediates and ultimately, Active Pharmaceutical Ingredients (APIs).

Sourcing Considerations for Buyers

When looking to buy 5-Amino-2,3-dichloropyridine, procurement managers and R&D scientists must prioritize quality, consistency, and reliability. Sourcing from established manufacturers in China offers several advantages, including competitive pricing and access to large-scale production capabilities. Key considerations include:

  • Purity Levels: Ensure the supplier can consistently provide material meeting your required purity specifications, typically above 98%.
  • Manufacturer Reputation: Partner with experienced manufacturers known for their quality control and adherence to international standards.
  • Supply Chain Stability: Confirm the supplier's capacity to meet demand fluctuations and ensure timely deliveries.
  • Technical Support: A reliable manufacturer will offer technical data sheets (TDS), Certificates of Analysis (CoA), and responsive customer service.

Finding a Reliable Supplier

For those seeking to purchase 5-Amino-2,3-dichloropyridine, identifying a reputable supplier is the first step. Many Chinese chemical manufacturers specialize in pharmaceutical intermediates and offer this compound. By conducting thorough research and requesting quotes, buyers can compare offerings based on price, quality, and service. For example, inquiring about sample availability is a standard practice to evaluate the product before committing to larger orders. The price of 5-Amino-2,3-dichloropyridine can vary based on purity and order volume, so it’s advisable to obtain multiple quotes to secure the best value.

In conclusion, 5-Amino-2,3-dichloropyridine is an indispensable intermediate for the pharmaceutical sector. By focusing on stringent quality requirements and partnering with reliable manufacturers, companies can ensure the integrity and efficiency of their synthesis processes.