In the dynamic field of organic chemistry, access to versatile and reliable chemical building blocks is essential for innovation. 5-Amino-2,3-dichloropyridine, identified by its CAS number 98121-41-6, is one such compound that offers significant utility for researchers and chemists alike. Its unique structure and reactivity make it a valuable component in a wide array of synthetic pathways.

Chemical Profile of 5-Amino-2,3-dichloropyridine

5-Amino-2,3-dichloropyridine is a substituted pyridine derivative, featuring an amino group at the 5th position and chlorine atoms at the 2nd and 3rd positions of the pyridine ring. This arrangement of functional groups dictates its chemical behavior, enabling it to participate in various coupling reactions, nucleophilic substitutions, and derivatizations. The compound typically presents as a solid, with a characteristic color ranging from white to light yellow or orange, indicating its purity. Its specific melting point, usually in the 107-112°C range, serves as a key quality parameter for formulators and chemists.

Applications in Organic Synthesis

The true value of 5-Amino-2,3-dichloropyridine lies in its broad applicability as a synthon. Chemists often leverage this compound in:

  • Heterocyclic Chemistry: As a pyridine derivative, it's foundational for creating more complex heterocyclic systems, which are prevalent in pharmaceuticals and agrochemicals.
  • Medicinal Chemistry: Researchers utilize it to synthesize novel drug candidates, exploring structure-activity relationships by modifying the pyridine core.
  • Material Science: Its potential use in developing new functional materials or polymers is an area of active investigation.

The ability to procure this intermediate from reliable manufacturers in China ensures that research and development projects can proceed without interruption. Understanding how to buy this compound and where to find competitive pricing from a reputable supplier is crucial for budget-conscious research initiatives.

Sourcing and Procurement Tips

For chemists and procurement specialists, sourcing 5-Amino-2,3-dichloropyridine involves looking for suppliers who can guarantee purity and consistent availability. When contacting a manufacturer, it's important to request detailed specifications, including CAS number, purity percentage (often expressed as GC purity), and physical appearance. Many suppliers offer this intermediate in various packaging sizes, from grams for initial research to kilograms for larger-scale synthesis. This flexibility is vital for R&D labs that may require small quantities for early-stage experiments or pilot production.

The Manufacturer's Advantage

Working directly with a manufacturer offers distinct advantages, such as potentially better pricing for bulk orders and direct access to quality control data. For example, a manufacturer in China can provide a free sample upon inquiry, allowing chemists to verify the product's suitability for their specific reaction conditions. This proactive approach to sourcing ensures that projects are well-supported by essential chemical reagents.

In essence, 5-Amino-2,3-dichloropyridine is a testament to the importance of specialized intermediates in advancing chemical research. Its accessibility through global supply chains empowers chemists to push the boundaries of synthetic innovation.