In the demanding world of pharmaceutical development and advanced organic synthesis, the consistent availability of high-purity chemical intermediates is paramount. Among these, 5-Bromo-2-iodopyrimidine (CAS 183438-24-6) stands out as a versatile and indispensable building block. For procurement managers and R&D scientists seeking to optimize their synthesis pathways, understanding the key attributes and reliable sourcing channels for this compound is crucial. This article aims to provide a comprehensive overview for those looking to buy 5-Bromo-2-iodopyrimidine, focusing on quality, applications, and the importance of selecting the right Chinese manufacturer and supplier.

Understanding 5-Bromo-2-iodopyrimidine: Chemical Profile and Significance

5-Bromo-2-iodopyrimidine, with the molecular formula C4H2BrIN2 and a molecular weight of approximately 284.88 g/mol, is distinguished by its unique pyrimidine ring structure functionalized with both bromine and iodine atoms. This dual halogenation is not merely a structural curiosity; it confers significant synthetic utility. The compound is particularly valued for its role in selective palladium-catalyzed cross-coupling reactions, such as Suzuki and Sonogashira couplings. These reactions are foundational in modern organic chemistry, enabling the efficient construction of complex molecular architectures. For professionals in pharmaceutical research, this translates directly into a powerful tool for developing novel therapeutic agents, including those targeting cancer and infectious diseases.

Applications Driving Demand: From Pharmaceuticals to Materials Science

The primary driver for the demand of 5-Bromo-2-iodopyrimidine is its application as a key intermediate in pharmaceutical synthesis. Researchers utilize it to create advanced drug candidates, leveraging its reactivity to build complex heterocyclic systems. Beyond pharmaceuticals, its utility extends to material science, where its structure can be modified to impart specific electronic or optical properties to polymers and other advanced materials. For any chemist or procurement specialist involved in drug discovery, agrochemical development, or the synthesis of specialty fine chemicals, having a reliable source for this compound is essential.

Sourcing Strategies: Choosing a Reputable Chinese Manufacturer and Supplier

When looking to purchase 5-Bromo-2-iodopyrimidine, especially in bulk quantities, identifying a trustworthy Chinese manufacturer and supplier is a critical step. The price and quality can vary significantly, and a dependable partner ensures not only cost-effectiveness but also the purity and consistency required for sensitive research and manufacturing processes. Key factors to consider when evaluating suppliers include their production capacity, adherence to quality control standards (such as ISO certifications), and their ability to provide comprehensive documentation, including certificates of analysis (COA). A manufacturer with proven expertise in continuous flow processes and large-scale production is often preferred for ensuring supply chain stability and competitive pricing.

Navigating the Purchase: Key Considerations for Buyers

For procurement managers and R&D scientists, the process of buying 5-Bromo-2-iodopyrimidine involves more than just finding the lowest price. It's about securing a supply of a high-purity intermediate that meets stringent specifications. When contacting potential manufacturers and suppliers, it is advisable to inquire about product purity (often specified as >97% or >99% by HPLC), available packaging sizes, lead times for delivery, and payment terms. Understanding the supplier's geographical location and proximity to major shipping ports, like Shanghai or Qingdao, can also be beneficial for optimizing logistics. Ultimately, building a relationship with a manufacturer that prioritizes quality, technical support, and reliable delivery is key to successful project execution.

In conclusion, 5-Bromo-2-iodopyrimidine is a cornerstone chemical for innovative research and development. By focusing on reputable Chinese suppliers and manufacturers, procurement specialists can ensure they obtain this vital intermediate at a competitive price, with the high purity and consistent quality necessary to drive advancements in pharmaceuticals and beyond. Your strategic sourcing decisions today will shape the success of your chemical synthesis endeavors tomorrow.